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Titolo:
Estrogen use among nursing home residents with a diagnosis of Parkinson's disease
Autore:
Fernandez, HH; Lapane, KL;
Indirizzi:
Brown Univ, Sch Med, Dept Clin Neurosci, Providence, RI 02912 USA Brown Univ Providence RI USA 02912 lin Neurosci, Providence, RI 02912 USA Brown Univ, Sch Med, Dept Community Hlth, Providence, RI 02912 USA Brown Univ Providence RI USA 02912 mmunity Hlth, Providence, RI 02912 USA Brown Univ, Sch Med, Ctr Gerontol & Hlth Care Res, Providence, RI 02912 USA Brown Univ Providence RI USA 02912 lth Care Res, Providence, RI 02912 USA Mem Hosp Rhode Isl, Div Neurol, Pawtucket, RI 02860 USA Mem Hosp Rhode Isl Pawtucket RI USA 02860 Neurol, Pawtucket, RI 02860 USA
Titolo Testata:
MOVEMENT DISORDERS
fascicolo: 6, volume: 15, anno: 2000,
pagine: 1119 - 1124
SICI:
0885-3185(200011)15:6<1119:EUANHR>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
MINIMUM DATA SET; DEMENTIA-ALZHEIMERS TYPE; REPLACEMENT THERAPY; POSTMENOPAUSAL WOMEN; OLDER WOMEN; GERIATRIC PHARMACOEPIDEMIOLOGY; ASSESSMENT INSTRUMENT; DOPAMINE-RECEPTORS; RISK; ESTRADIOL;
Keywords:
estrogen; Parkinson's disease; dementia; behavior; nursing home; long-term care; pharmacoepidemiology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
96
Recensione:
Indirizzi per estratti:
Indirizzo: Fernandez, HH Mem Hosp Rhode Isl, Div Neurol, 111 Brewster St, Pawtucket, RI 02860 USA Mem Hosp Rhode Isl 111 Brewster St Pawtucket RI USA 02860 SA
Citazione:
H.H. Fernandez e K.L. Lapane, "Estrogen use among nursing home residents with a diagnosis of Parkinson's disease", MOVEMENT D, 15(6), 2000, pp. 1119-1124

Abstract

BACKGROUND: The role of estrogen in motor, cognitive, and behavioral functions in Parkinson's disease (PD) remains unclear. OBJECTIVES/METHODS: To determine differences in functional, cognitive, andbehavioral patterns between estrogen users and non-users, we performed an observational study on 10,145 elderly women with PD using the Systematic Assessment in Geriatric drug use via Epidemiology (SAGE) database. The SAGE database consists of the Minimum Data Set (MDS), data collected on a cross-section of over 400,000 nursing home (NH) residents in five US states. Usinga cross-sectional study design, we evaluated the demographics, physical and cognitive function, and mortality rates of women with PD who received estrogen (n = 195) versus those who did not receive estrogen (n = 9950). RESULTS: Independent of age, estrogen users were less cognitively impairedand more independent in their activities of daily living. Surprisingly, more estrogen users were depressed and more likely to be on an antidepressantthan non-users. One-year death rates were comparable between estrogen users and non-users. CONCLUSION: This study supports the growing number of recent data suggesting estrogen's potential beneficial effects on PD motor and cognitive functions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 05:16:41