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Titolo:
Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(3-methyl-1-piperazinyl)quinoxalines
Autore:
Abdel-Jalil, RJ; Al-Qawasmeh, RA; Voelter, W; Heeg, P; El-Abadelah, MM; Sabri, SS;
Indirizzi:
Univ Tubingen, Inst Physiol Chem, Phys Biochem Abt, D-72076 Tubingen, Germany Univ Tubingen Tubingen Germany D-72076 em Abt, D-72076 Tubingen, Germany Univ Kliniken, Klin Hyg, D-72076 Tubingen, Germany Univ Kliniken Tubingen Germany D-72076 in Hyg, D-72076 Tubingen, Germany Univ Jordan, Fac Sci, Dept Chem, Amman, Jordan Univ Jordan Amman JordanUniv Jordan, Fac Sci, Dept Chem, Amman, Jordan
Titolo Testata:
JOURNAL OF HETEROCYCLIC CHEMISTRY
fascicolo: 5, volume: 37, anno: 2000,
pagine: 1273 - 1275
SICI:
0022-152X(200009/10)37:5<1273:SAPOS2>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
AGENTS; ANTIBACTERIALS; RECEPTOR; ACIDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Voelter, W Univ Tubingen, Inst Physiol Chem, Phys Biochem Abt, Hoppe Seyler Str 4, D-72076 Tubingen, Germany Univ Tubingen Hoppe Seyler Str 4 Tubingen Germany D-72076 many
Citazione:
R.J. Abdel-Jalil et al., "Synthesis and properties of some 2,3-disubstituted 6-fluoro-7-(3-methyl-1-piperazinyl)quinoxalines", J HETERO CH, 37(5), 2000, pp. 1273-1275

Abstract

The 2,3-disubstituted 6-fluoro-7-(4-methyl-1-piperazinyl)- quinoxalines (3-11) were synthesized for bioassay via reaction of 1,2-diamino-4-fluoro-5-(4-methyl-1-piperazinyl)benzene (2) with the appropriate 1,2-dicarbonyl compounds. However, none of the tested compounds 3-11 showed significant in vitro activity against E. coli ATCC 11229, S. aureus ATCC6538 and C. albicans SATCC10231.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 08:13:04