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Titolo:
Novel approaches to the treatment of acute renal failure
Autore:
Venkataraman, R; Kellum, JA;
Indirizzi:
Univ Pittsburgh, Med Ctr, Div Crit Care Med, Pittsburgh, PA 15261 USA UnivPittsburgh Pittsburgh PA USA 15261 are Med, Pittsburgh, PA 15261 USA
Titolo Testata:
EXPERT OPINION ON INVESTIGATIONAL DRUGS
fascicolo: 11, volume: 9, anno: 2000,
pagine: 2579 - 2592
SICI:
1354-3784(200011)9:11<2579:NATTTO>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE TUBULAR-NECROSIS; ATRIAL-NATRIURETIC-PEPTIDE; ADENOSINE ANTAGONIST THEOPHYLLINE; DOPAMINE-RECEPTOR AGONIST; CALCIUM-CHANNEL BLOCKER; GROWTH-FACTOR-I; BLOOD-FLOW; CONTRAST-MEDIA; INDUCED NEPHROPATHY; PROTECTIVE ROLE;
Keywords:
acute renal failure; adenosine receptor blockers; atrial natriuretic peptide analogues; calcium-channel blockers; dopamine receptor agonists; endothelin receptor antagonists; growth factors;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
129
Recensione:
Indirizzi per estratti:
Indirizzo: Kellum, JA Univ Pittsburgh, Med Ctr, Div Crit Care Med, Scaife Hall,Room 606C,3550 Terrace St, Pittsburgh, PA 15261 USA Univ Pittsburgh Scaife Hall,Room 606C,3550 Terrace St Pittsburgh PA USA 15261
Citazione:
R. Venkataraman e J.A. Kellum, "Novel approaches to the treatment of acute renal failure", EXPERT OP I, 9(11), 2000, pp. 2579-2592

Abstract

Acute renal failure (ARF) occurs frequently in hospitalised patients and is associated with significant morbidity and mortality. Many therapeutic strategies have been undertaken both to prevent acute renal injury and, once ARF occurs, to improve renal function and reduce mortality. Among the available pharmacological options, no specific therapy has been shown to alter the course of ARF. This article reviews the efficacy of several strategies inexperimental renal disease and raises the possibility that similar interventions might be available to the clinician in the near future for the prevention and management of ARF. The prospect of these novel strategies together with the ever-increasing understanding of the complex pathophysiology of ARF, offers the promise of effective and more physiological therapeutic interventions in this new millennium.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:13:53