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Titolo:
Articulatory/phonetic sequencing at the level of the anterior perisylvian cortex: A functional magnetic resonance imaging (fMRI) study
Autore:
Riecker, A; Ackermann, H; Wildgruber, D; Meyer, J; Dogil, G; Haider, H; Grodd, W;
Indirizzi:
Univ Tubingen, Dept Neurol, D-72076 Tubingen, Germany Univ Tubingen Tubingen Germany D-72076 Neurol, D-72076 Tubingen, Germany Univ Tubingen, CNS, Sect Expt Magnet Resonance Imaging, Dept Neuroradiol, D-72076 Tubingen, Germany Univ Tubingen Tubingen Germany D-72076 radiol, D-72076 Tubingen, Germany Univ Stuttgart, Dept Expt Phonet, D-7000 Stuttgart, Germany Univ Stuttgart Stuttgart Germany D-7000 honet, D-7000 Stuttgart, Germany Salzburg Univ, Dept Linguist, A-5020 Salzburg, Austria Salzburg Univ Salzburg Austria A-5020 Linguist, A-5020 Salzburg, Austria
Titolo Testata:
BRAIN AND LANGUAGE
fascicolo: 2, volume: 75, anno: 2000,
pagine: 259 - 276
SICI:
0093-934X(200011)75:2<259:ASATLO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY MOTOR CORTEX; ATAXIC DYSARTHRIA; SPEECH PRODUCTION; BRAIN; DISORDERS; LANGUAGE; ACTIVATION; APHASIA; ARTICULATION; PERFORMANCE;
Keywords:
apraxia of speech; aphemia; speech motor control; articulation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
59
Recensione:
Indirizzi per estratti:
Indirizzo: Ackermann, H Univ Tubingen, Dept Neurol, Hoppe Seyler Str 3, D-72076 Tubingen, Germany Univ Tubingen Hoppe Seyler Str 3 Tubingen Germany D-72076 ny
Citazione:
A. Riecker et al., "Articulatory/phonetic sequencing at the level of the anterior perisylvian cortex: A functional magnetic resonance imaging (fMRI) study", BRAIN LANG, 75(2), 2000, pp. 259-276

Abstract

Damage to the anterior peri-intrasylvian cortex of the dominant hemispheremay give rise to a fairly consistent syndrome of articulatory deficits in the absence of relevant paresis of orofacial or laryngeal muscles (apraxia of speech, aphemia, or phonetic disintegration). The available clinical data are ambiguous with respect to the relevant lesion site, indicating eitherdysfunction of the premotor aspect of the lower precentral gyrus or the anterior insula in the depth of the Sylvian fissure. In order to further specify the functional anatomic substratum of this syndrome, functional magnetic resonance imaging (fMRI) was performed during reiteration of syllables differing in their demands on articulatory/phonetic sequencing (CV versus CCCV versus CVCVCV). Horizontal tongue movements and a polysyllabic lexical item served as control conditions. Repetition of the CV and CCCV monosyllables elicited a rather bilateral symmetric hemodynamic response at the level of the anterior and posterior bank of the central sulcus (primary sensorimotor cortex), whereas a more limited area of neural activity arose within this domain during production of lexical and nonlexical polysyllables, significantly or exclusively lateralized toward the left hemisphere. There is neurophysiological evidence that primary sensorimotor cortex mediates the "fractionation" of movements. Assuming that the polysyllables considered are organized as coarticulated higher-order units, the observed restricted and lateralized cortical activation pattern, most presumably, reflects a mode of "nonindividualized'' motor control posing fewer demands on "movement fractionation. '' These findings may explain the clinical observation of disproportionately worse repetition of trisyllabic items as compared to monosyllablesin apraxia of speech. The various test materials failed to elicit significant activation of the anterior insula. If at all, only horizontal tongue movements yielded a hemodynamic reaction extending beyond the sensorimotor cortex to premotor areas. Since Limbic projections target the inferior dorsolateral frontal lobe, the enlarged region of activation during horizontal tongue movements might reflect increased attentional requirements of this task. (C) 2000 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 03:14:27