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Titolo:
Functional evaluation of hydronephrosis by diffusion-weighted MR imaging -Relationship between apparent diffusion coefficient and split glomerular filtration rate
Autore:
Toyoshima, S; Noguchi, K; Seto, H; Shimizu, M; Watanabe, N;
Indirizzi:
Toyama Med & Pharmaceut Univ, Dept Radiol, Toyama 9300194, Japan Toyama Med & Pharmaceut Univ Toyama Japan 9300194 Toyama 9300194, Japan
Titolo Testata:
ACTA RADIOLOGICA
fascicolo: 6, volume: 41, anno: 2000,
pagine: 642 - 646
SICI:
0284-1851(200011)41:6<642:FEOHBD>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAGNETIC-RESONANCE; RENAL-FUNCTION; KIDNEY; PERFUSION; MOTION; DTPA;
Keywords:
kidney, hydronephrosis; MR imaging, echo planar; diffusion study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Toyoshima, S Toyama Med & Pharmaceut Univ, Dept Radiol, 2630 Sugitani, Toyama 9300194, Japan Toyama Med & Pharmaceut Univ 2630 Sugitani Toyama Japan9300194
Citazione:
S. Toyoshima et al., "Functional evaluation of hydronephrosis by diffusion-weighted MR imaging -Relationship between apparent diffusion coefficient and split glomerular filtration rate", ACT RADIOL, 41(6), 2000, pp. 642-646

Abstract

Purpose: To determine the relationship between apparent diffusion coefficient (ADC) values measured by diffusion-weighted MR imaging and split renal function determined by renal scintigraphy in patients with hydronephrosis. Material and Methods: Diffusion-weighted imaging on a 1.5 T MR unit and renal scintigraphy were performed in 36 patients with hydronephrosis (45 hydronephrotic kidneys, 21 non-hydronephrotic kidneys). ADC values of the individual kidneys were measured by diffusion-weighted MR imaging. Split renal function (glomerular filtration rate (GFR)) was determined by renal scintigraphy using Tc-99m-DTPA. The relationship between ADC values and split GFR was examined in 66 kidneys. The hydronephrotic kidneys were further classified into three groups (severe renal dysfunction, GFR <10 ml/min, n=7; moderate renal dysfunction, GFR 10-25 ml/min, n=10; normal renal function, GFR >25 ml/min, n=28), and mean values for ADCs were calculated. Results: In hydronephrotic kidneys, there was a moderate positive correlation between ADC values and split GFR (R-2=0.56). On the other hand, in nonhydronephrotic kidneys, poor correlation between ADC values and split GFR was observed (R-2=0.08). The mean values for ADCs of the dysfunctioning hydronephrotic kidneys (severe renal dysfunction, 1.32x10(-3)+/-0.18x10(-3) mm(2)/s; moderate renal dysfunction, 1.38x10(-3)+/-0.10x10(-3) mm(2)/s) were significantly lower than that of the normal functioning hydronephrotic kidneys (1.63x10(-3)+/-0.12+/-10(-3) mm(2)/s). Conclusion: These results indicated that measurement of ADC values by diffusion-weighted MR imaging has a potential value in the evaluation of the functional status of hydronephrotic kidneys.

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Documento generato il 30/05/20 alle ore 14:34:42