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Titolo:
Chemical products toxic for the olfactory system: analysis and description
Autore:
Nores, JM; Biacabe, B; Bonfils, P;
Indirizzi:
Hop Raymond Poincare, Serv Med Interne, F-92380 Carches, France Hop Raymond Poincare Carches France F-92380 rne, F-92380 Carches, France Univ Paris 05, Hop Boucicaut, Fac Necker Enfants Malades, Serv ORL & Chirurg Cerv Faciale, Paris, France Univ Paris 05 Paris France rv ORL & Chirurg Cerv Faciale, Paris, France
Titolo Testata:
PRESSE MEDICALE
fascicolo: 32, volume: 29, anno: 2000,
pagine: 1773 - 1781
SICI:
0755-4982(20001028)29:32<1773:CPTFTO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
FRE
Soggetto:
INHALATION EXPOSURE; THRESHOLD SHIFT; MUCOSAL DAMAGE; NASAL-MUCOSA; F344 RATS; MICE; TRICHLOROETHYLENE; FORMALDEHYDE; DISORDERS; SYMPTOMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
77
Recensione:
Indirizzi per estratti:
Indirizzo: Nores, JM Hop Raymond Poincare, Serv Med Interne, 104 Blvd Raymond Poincare, F-92380Carches, France Hop Raymond Poincare 104 Blvd Raymond Poincare Carches France F-92380
Citazione:
J.M. Nores et al., "Chemical products toxic for the olfactory system: analysis and description", PRESSE MED, 29(32), 2000, pp. 1773-1781

Abstract

An important problem: Occupational exposure to chemical products can have toxic effects on the olfactory system. An important number of patients haveexperienced olfactory disorders subsequent to the development of the chemical industry and atmospheric pollution. Epidemiology data: Straightforward data are difficult to collect because several cofactors other than the toxic product are involved. Two lists of toxic products can be made. The first list includes products for which scientific data is available and the second products for which data is lacking. Olfactory tests also differ between authors and countries. Two types of toxicity: Acute, accidental toxicity is evidenced by the lesions caused by inhalation of high-doses of strongly toxic agents. Chronic intoxication caused by lower concentrations of these inhaled agents does not produce a trigeminal reflex leading to a modified respiratory rate reducingthe airborne aggression. Approximations: Clinical data describing the olfactory toxicity of certainindustrial and chemical compounds are very significant but often cannot prove a cause and effect relationship. Data obtained with experimental modelsin rodents are difficult to extrapolate to humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 04:39:49