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Titolo:
Correlations of elevated levels of hexacosanoate in erythrocyte membranes with risk factors for atherosclerosis
Autore:
Antoku, Y; Tsukamoto, K; Miyoshi, Y; Nagino, H; Anezaki, M; Suwa, K; Narabe, Y;
Indirizzi:
Natl Chikugo Hosp, Dept Neurol, Chikugo, Fukuoka 8330054, Japan Natl Chikugo Hosp Chikugo Fukuoka Japan 8330054 o, Fukuoka 8330054, Japan Meiji Mutual Life Insurance Co, Chiyoda Ku, Tokyo 1000005, Japan Meiji Mutual Life Insurance Co Tokyo Japan 1000005 Tokyo 1000005, Japan Lab BML Inc, Kawagoe, Saitama 3501101, Japan Lab BML Inc Kawagoe Saitama Japan 3501101 Kawagoe, Saitama 3501101, Japan
Titolo Testata:
ATHEROSCLEROSIS
fascicolo: 1, volume: 153, anno: 2000,
pagine: 169 - 173
SICI:
0021-9150(200011)153:1<169:COELOH>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; DENSITY-LIPOPROTEIN CHOLESTEROL; FATTY-ACID ANALYSIS; LONG-CHAIN; SERUM-CHOLESTEROL; ADRENOLEUKODYSTROPHY; PLASMA; FRAMINGHAM; OXIDATION; LIPIDS;
Keywords:
erythrocyte membranes; hexacosanoate; atherosclerosis; age;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Antoku, Y Natl Chikugo Hosp, Dept Neurol, 515 Kurakazu, Chikugo, Fukuoka 8330054, Japan Natl Chikugo Hosp 515 Kurakazu Chikugo Fukuoka Japan 8330054 pan
Citazione:
Y. Antoku et al., "Correlations of elevated levels of hexacosanoate in erythrocyte membranes with risk factors for atherosclerosis", ATHEROSCLER, 153(1), 2000, pp. 169-173

Abstract

We analyzed erythrocyte membrane C26:0 from 504 volunteers by high-performance liquid chromatography. The associations between the elevated levels oferythrocyte membrane C26:0 (0.20 or greater than 0.20%) and sex, obesity (body mass index greater than or equal to 26.4), smoking (greater than or equal to 20 cigarettes per day), present illnesses and past diseases were examined with the chi (2) test. The correlations among age and the levels of erythrocyte membrane C26:0, plasma total cholesterol, triglycerides, LDL cholesterol and HDL cholesterol were analyzed using Spearman's correlation coefficient. Moreover, the frequencies of high levels of erythrocyte membrane C26:0 were examined in male and female subjects divided into seven age groups. The elevated levels of erythrocyte membrane C26:0 were significantly more frequent in male subjects than in females, and were closely associated with obesity, smoking, and atherosclerosis-related diseases of present illnesses. The levels of erythrocyte membrane C26:0 were highly correlated with age and the levels of plasma total cholesterol, triglycerides and LDL cholesterol, and inversely with those of HDL cholesterol. The frequency of high levels of erythrocyte membrane C26:0 in male subjects was greater than thatin female subjects in all of the seven age groups. Elevated levels of erythrocyte membrane C26:0 may be closely related with atherosclerosis. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 16:20:58