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Titolo:
Hepatocellular carcinoma treated with percutaneous radio-frequency ablation: Usefulness of power Doppler US with a microbubble contrast agent in evaluating therapeutic response-preliminary results
Autore:
Choi, D; Lim, HK; Kim, SH; Lee, WJ; Jang, HJ; Lee, JY; Paik, SW; Koh, KC; Lee, JH;
Indirizzi:
Sung Kyun Kwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol,Kangnam Ku, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 , Seoul 135710, South Korea Sung Kyun Kwan Univ, Sch Med, Samsung Med Ctr, Dept Internal Med,Kangnam Ku, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710, Seoul 135710, South Korea
Titolo Testata:
RADIOLOGY
fascicolo: 2, volume: 217, anno: 2000,
pagine: 558 - 563
SICI:
0033-8419(200011)217:2<558:HCTWPR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIOFREQUENCY TISSUE ABLATION; ETHANOL INJECTION; LIVER METASTASES; HEPATIC METASTASES; FOLLOW-UP; COAGULATION; TUMORS; ELECTROCAUTERY; EXPERIENCE; RESECTION;
Keywords:
liver neoplasms, CT; liver neoplasms, US; radiofrequency (RF) ablation; ultrasound (US), contrast media; ultrasound (US), power Doppler studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Lim, HK Sung Kyun Kwan Univ, Sch Med, Samsung Med Ctr, Dept Radiol,KangnamKu, Seoul 135710, South Korea Sung Kyun Kwan Univ Seoul South Korea 135710 135710, South Korea
Citazione:
D. Choi et al., "Hepatocellular carcinoma treated with percutaneous radio-frequency ablation: Usefulness of power Doppler US with a microbubble contrast agent in evaluating therapeutic response-preliminary results", RADIOLOGY, 217(2), 2000, pp. 558-563

Abstract

PURPOSE: To evaluate the usefulness of power Doppler ultrasonography (US) with a microbubble contrast agent in assessing the therapeutic response of hepatocellular carcinomas (HCCs) treated with percutaneous radio-frequency (RF) ablation. MATERIALS AND METHODS: Forty patients with 45 nodular HCC lesions 1.0-3.8 cm in diameter underwent power Doppler US before and after intravenous injection of a microbubble contrast agent. The same procedures were repeated after US-guided percutaneous RF ablation. The results of these studies were compared with those of three-phase helical computed tomography (CT) performed immediately after RF ablation. RESULTS: Before RF ablation, nonenhanced power Doppler US demonstrated flow signals within tumor in 33 of 45 HCCs. After contrast agent administration, flow signals increased or newly appeared in all cases. After RF ablation, none of the ablated tumors showed intratumoral flow signals at nonenhanced power Doppler US, whereas six showed marginal intratumoral flow signals at contrast agent-enhanced power Doppler US. These six tumors were found to have small enhancing foci, suggestive of viable tumor, in corresponding areas at immediate follow-up CT. Additional RF ablation or transcatheter arterial chemoembolization was performed in these tumors. CONCLUSION: The results of power Doppler US with a microbubble contrast agent in HCCs treated with RF ablation correlated well with those of contrast-enhanced CT. Preliminary data suggest that contrast-enhanced power DopplerUS can be a promising noninvasive technique for assessing therapeutic response.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 19:31:13