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Titolo:
Classical chemotherapy for metastatic melanoma
Autore:
Becker, JC; Kampgen, E; Brocker, EB;
Indirizzi:
Univ Wurzburg, Hautklin, Dept Dermatol, D-97080 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97080 rmatol, D-97080 Wurzburg, Germany
Titolo Testata:
CLINICAL AND EXPERIMENTAL DERMATOLOGY
fascicolo: 6, volume: 25, anno: 2000,
pagine: 503 - 508
SICI:
0307-6938(200010)25:6<503:CCFMM>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADVANCED MALIGNANT-MELANOMA; UVEAL MELANOMA; PROGNOSTIC FACTORS; PHASE-II; DACARBAZINE; CISPLATIN; TRIAL; FOTEMUSTINE; THERAPY; INTERLEUKIN-2;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Becker, JC Univ Wurzburg, Hautklin, Dept Dermatol, Josef Schneider Str 2, D-97080 Wurzburg, Germany Univ Wurzburg Josef Schneider Str 2 Wurzburg Germany D-97080 y
Citazione:
J.C. Becker et al., "Classical chemotherapy for metastatic melanoma", CLIN EXP D, 25(6), 2000, pp. 503-508

Abstract

Despite a major effort in clinical research scrutinizing various treatmentregimens for patients suffering from metastatic melanoma the prognosis forthese patients still remains poor. The treatment options tested have ranged from monochemotherapy, polychemotherapeutic approaches including highly toxic regimens requiring autologous bone marrow rescue, immuno-modulatory therapies, e.g. defined cytokines such as interferon-alpha and interleukin-2 as well as vaccination therapy with dendritic cells or genetically modifiedtumour cells, and bio-chemotherapy. Although immuno-modulatory approaches are currently regarded as the most promising, to date no improved overall survival has been achieved by any of these measures especially if tested in large multicentre trials. The focus of this review will be on classical chemotherapy with emphasis on both cutaneous and uveal melanoma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/10/20 alle ore 10:18:14