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Titolo:
Proton magnetic resonance spectroscopy (H-1-MRS) in ALS
Autore:
Pioro, EP;
Indirizzi:
Cleveland Clin Fdn, Ctr ALS & Related Disorders, Sect Neuromuscular Dis & EMG, Cleveland, OH 44195 USA Cleveland Clin Fdn Cleveland OH USA 44195 & EMG, Cleveland, OH 44195 USA
Titolo Testata:
AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MOTOR NEURON DISORDERS
, volume: 1, anno: 2000, supplemento:, 2
pagine: S7 - S16
SICI:
1466-0822(200006)1:<S7:PMRS(I>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMYOTROPHIC-LATERAL-SCLEROSIS; MOTOR-NEURON DISEASE; IN-VIVO; N-ACETYLASPARTATE; MR SPECTROSCOPY; BRAIN; CORTEX;
Keywords:
H-1-MRS; upper motor neuron dysfunction; neurological disorders; diagnosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Pioro, EP Cleveland Clin Fdn, Ctr ALS & Related Disorders, Sect Neuromuscular Dis & EMG, S90,9500 Euclid Ave, Cleveland, OH 44195 USA Cleveland Clin Fdn S90,9500 Euclid Ave Cleveland OH USA 44195 SA
Citazione:
E.P. Pioro, "Proton magnetic resonance spectroscopy (H-1-MRS) in ALS", AMYOTROPH L, 1, 2000, pp. S7-S16

Abstract

Establishing the presence of upper motor neuron (UMN) pathology is essential for an accurate and definite diagnosis of ALS, However, clinical identification of UMN dysfunction can be difficult in early disease or if lower motor neuron signs are prominent. A routine technique such as magnetic resonance imaging is usually normal and non-specific. Proton magnetic resonance spectroscopy (H-1-MRS) is a non-invasive neuroimaging technique that has successfully demonstrated evidence of neuronal abnormalities in motor regions of the brain in ALS. This review discusses the advantages and limitations of employing H-1-MRS as an investigative tool in the diagnosis of ALS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 09:54:37