Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Toxicity testing of senna occidentalis seed in rabbits
Autore:
Tasaka, AC; Weg, R; Calore, EE; Sinhorini, IL; Dagli, MLZ; Haraguchi, M; Gorniak, SL;
Indirizzi:
Univ Sao Paulo, Fac Vet Med, Dept Pathol, Res Ctr Vet Toxicol, Sao Paulo, Brazil Univ Sao Paulo Sao Paulo Brazil Res Ctr Vet Toxicol, Sao Paulo, Brazil Emilio Ribas Inst, Dept Pathol, Sao Paulo, Brazil Emilio Ribas Inst Sao Paulo Brazil Inst, Dept Pathol, Sao Paulo, Brazil Inst Biol, Sao Paulo, Brazil Inst Biol Sao Paulo BrazilInst Biol, Sao Paulo, Brazil
Titolo Testata:
VETERINARY RESEARCH COMMUNICATIONS
fascicolo: 8, volume: 24, anno: 2000,
pagine: 573 - 582
SICI:
0165-7380(200012)24:8<573:TTOSOS>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
CASSIA-OCCIDENTALIS; LEG CAES; EXPERIMENTAL INTOXICATION; MITOCHONDRIAL MYOPATHY; POISONED RABBITS; CHICKS; CATTLE;
Keywords:
cytochrome oxidase; electron microscopy; histochemistry; rabbits; seed; Senna occidentalis; serum enzymes; serum proteins; toxicity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Tasaka, AC USP, Fac Med Vet & Zootecnia, Av Prof Orlando Marques de Paiva 87, BR-05508000 Sao Paulo, Brazil USP Av Prof Orlando Marques de Paiva 87 Sao Paulo Brazil BR-05508000 BC
Citazione:
A.C. Tasaka et al., "Toxicity testing of senna occidentalis seed in rabbits", VET RES COM, 24(8), 2000, pp. 573-582

Abstract

The effect was investigated of administering ground Senna occidentalis seeds to rabbits in different concentrations (1%, 2%, 3% and 4%) in the ration. The experiment lasted 30 days and the toxic effects of the plant were evaluated on the basis of weight gain, histopathological, biochemical and morphometric parameters, as well as histochemistry and electron microscopy. Animals that received the ration containing 4% ground S. occidentalis seeds gained less weight (p <0.05) and died in the third week. Histopathology revealed that the heart and liver were the main organs affected, with myocardialnecrosis and centrolobular degeneration. There was a reduction in cytochrome oxidase activity in the glycogenolytic fibres, together with muscle atrophy, confirmed by the morphometric studies. Electron microscopy of the liver cells revealed dilated mitochondria, with destruction of the internal cristae.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/02/20 alle ore 20:58:20