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Titolo:
Adhesion complexes implicated in intestinal epithelial cell-matrix interactions
Autore:
Stutzmann, J; Bellissent-Waydelich, A; Fontao, L; Launay, JF; Simon-Assmann, P;
Indirizzi:
INSERM Res Unit 381, F-67200 Strasbourg, France INSERM Res Unit 381 Strasbourg France F-67200 F-67200 Strasbourg, France
Titolo Testata:
MICROSCOPY RESEARCH AND TECHNIQUE
fascicolo: 2, volume: 51, anno: 2000,
pagine: 179 - 190
SICI:
1059-910X(20001015)51:2<179:ACIIIE>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLON-CARCINOMA CELLS; INTEGRIN BETA-4 SUBUNIT; ACTIN STRESS FIBERS; CYTOPLASMIC DOMAIN; FOCAL ADHESIONS; CLEAVAGE FURROW; ENTEROCYTIC DIFFERENTIATION; MICROTUBULE DISRUPTION; HEMIDESMOSOMAL PLAQUE; EPIDERMOLYSIS-BULLOSA;
Keywords:
intestine; colonic cancer cells; focal adhesion; hemidesmosome; integrin; extracellular matrix;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
109
Recensione:
Indirizzi per estratti:
Indirizzo: Simon-Assmann, P INSERM Res Unit 381, 3 Ave Moliere, F-67200 Strasbourg, France INSERM Res Unit 381 3 Ave Moliere Strasbourg France F-67200
Citazione:
J. Stutzmann et al., "Adhesion complexes implicated in intestinal epithelial cell-matrix interactions", MICROSC RES, 51(2), 2000, pp. 179-190

Abstract

This article review summarizes data on cell-substratum adhesion complexes involved in the regulation of cellular functions in the intestine. We firstfocus on the molecular composition of the two main adhesion structures-thebeta 1 integrin-adhesion complex and the hemidesmosome-found in vivo and in two human intestinal cell lines. We also report the key findings on the cellular behavior and response to the extracellular matrix that involve integrins, the main transmembrane anchors of these complexes. How the dynamics of cell/extracellular matrix interactions contribute to cell migration, proliferation, differentiation, and tumorigenicity is discussed in the light of the data provided by the human intestinal cells. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 14:37:46