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Titolo:
The significance of functioning gallbladder visualization on hepatobiliaryscintigraphy in infants with persistent jaundice
Autore:
Lee, CH; Wang, PW; Lee, TT; Tiao, MM; Huang, FC; Chuang, JH; Shieh, CS; Cheng, YF;
Indirizzi:
Chang Gung Univ, Dept Nucl Med, Chang Gung Mem Hosp, Kaohsiung, Taiwan Chang Gung Univ Kaohsiung Taiwan Chang Gung Mem Hosp, Kaohsiung, Taiwan Chang Gung Univ, Dept Pediat, Chang Gung Mem Hosp, Kaohsiung, Taiwan ChangGung Univ Kaohsiung Taiwan Chang Gung Mem Hosp, Kaohsiung, Taiwan Chang Gung Univ, Dept Pediat Surg, Chang Gung Mem Hosp, Kaohsiung, Taiwan Chang Gung Univ Kaohsiung Taiwan Chang Gung Mem Hosp, Kaohsiung, Taiwan Chang Gung Univ, Dept Diagnost Radiol, Chang Gung Mem Hosp, Kaohsiung, Taiwan Chang Gung Univ Kaohsiung Taiwan Chang Gung Mem Hosp, Kaohsiung, Taiwan
Titolo Testata:
JOURNAL OF NUCLEAR MEDICINE
fascicolo: 7, volume: 41, anno: 2000,
pagine: 1209 - 1213
SICI:
0161-5505(200007)41:7<1209:TSOFGV>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
BILIARY ATRESIA; NEONATAL CHOLESTASIS; DIAGNOSIS; DISIDA;
Keywords:
biliary atresia; biliary patency; hepatobiliary scintigraphy; abdominal sonography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, CH Chang Gung Univ, Dept Nucl Med, Chang Gung Mem Hosp, 123 Ta Pei Rd,Niao Sung Hsiang, Kaohsiung, Taiwan Chang Gung Univ 123 Ta Pei Rd,Niao Sung Hsiang Kaohsiung Taiwan
Citazione:
C.H. Lee et al., "The significance of functioning gallbladder visualization on hepatobiliaryscintigraphy in infants with persistent jaundice", J NUCL MED, 41(7), 2000, pp. 1209-1213

Abstract

The purpose of this study was to determine whether gallbladder visualization can help exclude biliary atresia in hepatobiliary scintigraphic studies of infants with persistent jaundice. Methods: One hundred fifty-two infantswith persistent jaundice (49 patients with a final diagnosis of biliary atresia and 103 with biliary patency) were studied using both hepatobiliary scintigraphy and abdominal sonography. Food was withheld for 4 h before the examination, and the infants were fed nothing but glucose until 6 h after the initial injection of Tc-99m-disofenin or until the gallbladder was seen.if the gallbladder was seen, the infants were fed milk, and imaging was continued to observe gallbladder contractility. Results: In none of the 49 patients with biliary atresia could the gallbladder be seen with hepatobiliary scintigraphy, but abdominal sonography revealed 9 normal-sized gallbladders. Of the 103 patients with biliary patency, hepatobiliary scintigraphy detected the gallbladder more frequently (74%, 76/103) than did abdominal sonography (63%, 65/103). All visualized gallbladders contracted after the infants were fed milk. If we include visualization of both the gallbladder andbowel radioactivity as criteria, the specificity of biliary atresia on hepatobiliary scintigraphy increases to 86% (89/103). Conclusion: Gallbladderswere usually visible on hepatobiliary scintigraphy of fasting patients with biliary patency. A functioning gallbladder, with or without visualizationof bowel radioactivity, indicated biliary patency.

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Documento generato il 19/09/20 alle ore 17:25:19