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Titolo:
Comparing filtered backprojection and ordered-subsets expectation maximization for small-lesion detection and localization in Ga-67 SPECT
Autore:
Wells, RG; King, MA; Simkin, PH; Judy, PF; Brill, AB; Gifford, HC; Licho, R; Pretorius, PH; Schneider, PB; Seldin, DW;
Indirizzi:
Univ Massachusetts, Med Ctr, Div Nucl Med, Worcester, MA 01655 USA Univ Massachusetts Worcester MA USA 01655 cl Med, Worcester, MA 01655 USA Brigham & Womens Hosp, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 mens Hosp, Boston, MA 02115 USA Lahey Clin Med Ctr, Burlington, MA 01803 USA Lahey Clin Med Ctr Burlington MA USA 01803 Ctr, Burlington, MA 01803 USA
Titolo Testata:
JOURNAL OF NUCLEAR MEDICINE
fascicolo: 8, volume: 41, anno: 2000,
pagine: 1391 - 1399
SICI:
0161-5505(200008)41:8<1391:CFBAOE>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
ATTENUATION COMPENSATION; NOISE PROPERTIES; OBSERVER PERFORMANCE; EM ALGORITHM; FDG PET; IMAGES; RECONSTRUCTION; TOMOGRAPHY; ROC; DETECTABILITY;
Keywords:
localization receiver operating characteristic; filtered backprojection; ordered-subsets expectation maximization; attenuation correction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Wells, RG Univ Massachusetts, Med Ctr, Div Nucl Med, Worcester, MA 01655 USA Univ Massachusetts Worcester MA USA 01655 rcester, MA 01655 USA
Citazione:
R.G. Wells et al., "Comparing filtered backprojection and ordered-subsets expectation maximization for small-lesion detection and localization in Ga-67 SPECT", J NUCL MED, 41(8), 2000, pp. 1391-1399

Abstract

Iterative reconstruction of SPECT images has recently become clinically available as an alternative to filtered backprojection (FBP). However, there is conflicting evidence on whether iterative reconstruction, such as with the ordered-subsets expectation maximization (OSEM) algorithm, improves diagnostic performance over FBP. The study objective was to determine if the detection and localization of small lesions in simulated thoracic gallium SPECT images are better with OSEM reconstruction than with FBP, both with and without attenuation correction (AC). Methods: Images were simulated using an analytic projector acting on the mathematic cardiac torso computer phantom. Perfect scatter rejection was assumed. Lesion detection accuracy was assessed using localization receiver operating characteristic methodology. Theimages were read by 5 nuclear medicine physicians. For each reconstructionstrategy and for each observer, data were collected in 2 viewing sessions of 100 images. Two-way ANOVA and, when indicated, the Scheffe multiple comparisons test were applied to check for significant differences. Results: Little difference in the accuracy of detection or localization was seen between FBP with and without AC. OSEM with AC extended the contrast range for accurate lesion detection and localization over that of the other methods investigated. Without AC, no significant difference between OSEM and FBP reconstruction was detected. Conclusion: OSEM with AC may improve the detection and localization of thoracic gallium-labeled lesions over FBP reconstruction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 21:07:48