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Titolo:
The neuronal response to electrical constant-amplitude pulse train stimulation: evoked compound action potential recordings
Autore:
Matsuoka, AJ; Abbas, PJ; Rubinstein, JT; Miller, CA;
Indirizzi:
Univ Iowa, Dept Otolaryngol Head & Neck Surg, Iowa City, IA 52246 USA UnivIowa Iowa City IA USA 52246 ead & Neck Surg, Iowa City, IA 52246 USA Univ Iowa, Dept Speech Pathol & Audiol, Iowa City, IA 52246 USA Univ IowaIowa City IA USA 52246 Pathol & Audiol, Iowa City, IA 52246 USA Univ Iowa, Dept Physiol & Biophys, Iowa City, IA 52246 USA Univ Iowa IowaCity IA USA 52246 ysiol & Biophys, Iowa City, IA 52246 USA
Titolo Testata:
HEARING RESEARCH
fascicolo: 1-2, volume: 149, anno: 2000,
pagine: 115 - 128
SICI:
0378-5955(200011)149:1-2<115:TNRTEC>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUDITORY-NERVE FIBERS; MONOPHASIC STIMULATION; CAT; MONOPOLAR;
Keywords:
pulse train; electrical stimulation; auditory nerve;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Matsuoka, AJ Univ Iowa, 127B SHC, Iowa City, IA 52242 USA Univ Iowa 127B SHC Iowa City IA USA 52242 City, IA 52242 USA
Citazione:
A.J. Matsuoka et al., "The neuronal response to electrical constant-amplitude pulse train stimulation: evoked compound action potential recordings", HEARING RES, 149(1-2), 2000, pp. 115-128

Abstract

The purpose of this study was to gain a greater understanding of the electrically evoked compound action potential (EAP) responses to pulse train stimulation. Analysis of EAP amplitude responses suggested that an alternatingpattern varied depending upon stimulus level, interpulse interval (IPI), stimulus waveform, and stimulus polarity. Stimulus level-dependent recovery was seen in the cat and the guinea pig. higher stimulus level tended to provide faster recovery. Both polarity-dependent recovery and polarity-dependent adaptation were observed in the cat and these stimulus polarity effects were less consistent in the guinea pig. The polarity-dependent recovery effect supports the hypothesis that anodal and cathodal stimuli excite different sites along auditory nerve fibers. Amplitude differences between the response to the second pulse and the steady-state response at the same IPI aresignificantly greater for anodal stimuli than for cathodal stimuli in all cats. These data suggest that there is a cumulative refractory effect in the auditory nerve of cats, especially in response to anodal stimuli. (C) 2000 Elsevier Science B.V. All rights reserved.

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Documento generato il 25/11/20 alle ore 00:42:54