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Titolo:
Delayed visual P3 in unilateral thalamic stroke
Autore:
Trinka, E; Unterrainer, J; Staffen, W; Loscher, NW; Ladurner, G;
Indirizzi:
Univ Innsbruck Hosp, Dept Neurol, A-6020 Innsbruck, Austria Univ InnsbruckHosp Innsbruck Austria A-6020 , A-6020 Innsbruck, Austria Christian Doppler Klin, Dept Neurol, Salzburg, Austria Christian Doppler Klin Salzburg Austria Dept Neurol, Salzburg, Austria
Titolo Testata:
EUROPEAN JOURNAL OF NEUROLOGY
fascicolo: 5, volume: 7, anno: 2000,
pagine: 517 - 522
SICI:
1351-5101(200009)7:5<517:DVPIUT>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVENT-RELATED POTENTIALS; TEMPORAL-LOBE EPILEPSY; INTRACEREBRAL POTENTIALS; RARE TARGET; DIAGNOSTICAL RELEVANCE; STIMULI; DEMENTIA; LESIONS; LOCALIZATION; CORTEX;
Keywords:
dementia; event-related potential; P3 latency; P3 potential; thalamic infarction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: Trinka, E Univ Innsbruck Hosp, Dept Neurol, Anichstr 35, A-6020 Innsbruck,Austria Univ Innsbruck Hosp Anichstr 35 Innsbruck Austria A-6020 ustria
Citazione:
E. Trinka et al., "Delayed visual P3 in unilateral thalamic stroke", EUR J NEUR, 7(5), 2000, pp. 517-522

Abstract

The P3 potential is accepted as a neurophysiological correlate of memory and attention. Delayed latencies were reported in different forms of dementias. Although the generator sites are still under debate, the thalamus may play a crucial role. The aim of this study was to investigate the influence of an unilateral thalamic ischaemic infarction on P3 generation. The event-related P3 component of six patients (2 male, four female; mean age 47 years, range 22-63 years) with unilateral thalamic ischaemic infarction was studied and compared to age-matched controls (five male, nine female; mean age 45.8 years; range 22-69 years). All patients underwent full clinical examination, CCT, and MRI scan. P3 potentials were recorded with a visual three stimulus discrimination paradigm. The mean P3 latency of the patient group to the target stimulus was delayed (469.7 ms, SD = 36.8) compared with the controls (378.8 ms, SD = 51.5; P < 0.05). The mean P3 latency tothe unexpected stimulus was delayed in patients with thalamic infarction compared with controls [477 ms (SD = 46.6) vs. 381.2 ms (SD = 48.5); P < 0.001). Delayed P3 components of the event-related potential (ERP) were recorded in six patients with unilateral thalamic infarction, suggesting an important role of the thalamus in the generation of the P3 potential.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 06:53:52