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Titolo:
Longitudinal study of methylmercury and inorganic mercury in blood and urine of pregnant and lactating women, as well as in umbilical cord blood
Autore:
Vahter, M; Akesson, A; Lind, B; Bjors, U; Schutz, A; Berglund, M;
Indirizzi:
Karolinska Inst, Inst Environm Med, S-17177 Stockholm, Sweden Karolinska Inst Stockholm Sweden S-17177 Med, S-17177 Stockholm, Sweden Univ Lund, Dept Occupat & Environm Med, S-22185 Lund, Sweden Univ Lund Lund Sweden S-22185 cupat & Environm Med, S-22185 Lund, Sweden
Titolo Testata:
ENVIRONMENTAL RESEARCH
fascicolo: 2, volume: 84, anno: 2000,
pagine: 186 - 194
SICI:
0013-9351(200010)84:2<186:LSOMAI>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
DENTAL AMALGAM FILLINGS; FISH CONSUMPTION; METALLIC MERCURY; METHYL MERCURY; BREAST-MILK; EXPOSURE; BRAIN; PLACENTA; NEURODEVELOPMENT; TRANSPORT;
Keywords:
mercury compounds; biomarkers of exposure; blood; urine; speciation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Vahter, M Karolinska Inst, Inst Environm Med, S-17177 Stockholm, Sweden Karolinska Inst Stockholm Sweden S-17177 177 Stockholm, Sweden
Citazione:
M. Vahter et al., "Longitudinal study of methylmercury and inorganic mercury in blood and urine of pregnant and lactating women, as well as in umbilical cord blood", ENVIR RES, 84(2), 2000, pp. 186-194

Abstract

We have investigated exposure to methylmercury (MeHg) and mercury vapor (Hg-0) in pregnant women and their newborns in Stockholm. The women were followed for 15 months post delivery. MeHg, inorganic Hg (I-Hg), and total Hg (I-Hg) in maternal and cord blood were determined by automated alkaline solubilization/reduction and cold vapor atomic fluorescence spectrometry. T-Hg in urine was determined by inductively coupled plasma mass spectrometry. About 72% of the Hg in blood (n = 148) in early pregnancy was MeHg (median 0.94 mug/L, maximum 6.8 mug/L). Blood MeHg decreased during pregnancy, partlydue to decreased intake of fish in accordance with recommendations to not eat certain predatory fish during pregnancy. Cord blood MeHg (median 1.4 mug/L, maximum 4.8 mug/L) was almost twice that in maternal blood in late pregnancy and was probably influenced by maternal MeHg exposure earlier and before pregnancy. Blood I-Hg (median 0.37 mug/L, maximum 4.2 mug/L) and urineT-Hg (median 1.6 mug/L, maximum 12 mug/L) in early pregnancy were highly correlated, and both were associated with the number of amalgam fillings. The concentrations decreased during lactation, probably due to excretion in milk. Cord blood I-Hg was correlated with that in maternal blood. The results show the importance of speciation of Hg in blood for evaluation of exposure and health risks. (C) 2000 Academic Press.

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Documento generato il 04/12/20 alle ore 22:30:52