Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Prospective randomized comparison of thoracoscopic talc poudrage under local anesthesia versus bleomycin instillation for pleurodesis in malignant pleural effusions
Autore:
Diacon, AH; Wyser, C; Bolliger, CT; Tamm, M; Pless, M; Perruchoud, AP; Soler, M;
Indirizzi:
Univ Basel Hosp, Dept Internal Med, Div Pulm, CH-4031 Basel, Switzerland Univ Basel Hosp Basel Switzerland CH-4031 lm, CH-4031 Basel, Switzerland
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 4, volume: 162, anno: 2000,
pagine: 1445 - 1449
SICI:
1073-449X(200010)162:4<1445:PRCOTT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
BORE CATHETER DRAINAGE; INTRACAVITARY BLEOMYCIN; RESPIRATORY-FAILURE; INSUFFLATED TALC; MANAGEMENT; SCLEROTHERAPY; TETRACYCLINE; CARCINOMA; SLURRY; TRIAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Soler, M Univ Basel Hosp, Dept Internal Med, Div Pulm, Petergraben 4, CH-4031 Basel, Switzerland Univ Basel Hosp Petergraben 4 Basel Switzerland CH-4031 tzerland
Citazione:
A.H. Diacon et al., "Prospective randomized comparison of thoracoscopic talc poudrage under local anesthesia versus bleomycin instillation for pleurodesis in malignant pleural effusions", AM J R CRIT, 162(4), 2000, pp. 1445-1449

Abstract

Induction of pleurodesis offers benefit for patients with metastatic tumors and symptomatic malignant pleural effusions, but the best method for achieving this is still unknown. In this prospective, randomized comparison of two well-established pleurodesis procedures, 36 patients with malignant pleural effusions, expanded lungs after drainage, and expected survival of > 1mo received either bleomycin instillation (60E) via a small-bore thoracostomy tube or thoracoscopic talc poudrage (5 g) under local anesthesia. Efficacy, safety, and cost could be evaluated for 32 treatments (17 bleomycin, 15 talc) in 31 patients. Recurrence rates of effusion with bleomycin and talc poudrage after 30 d were 41% and 13% (p = 0.12), respectively, those after 90 d were 59% and 13%, respectively (p = 0.01), and those after 180 d were 65% and 73% (p = 0.005), respectively. Neither procedure showed any majoradverse effect, and both were equally well tolerated. Cost estimation favored thoracoscopic talc poudrage, both for the initial hospitalization and with regard to recurrences. In conclusion, thoracoscopic talc pleurodesis under local anesthesia is superior to bleomycin instillation for pleurodesis in cases of malignant pleural effusion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 16:05:41