Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Frequency and significance of increased upper airway resistance during sleep
Autore:
Rees, K; Kingshott, RN; Wraith, PK; Douglas, NJ;
Indirizzi:
Univ Edinburgh, Royal Infirm NHS Trust, Sleep Ctr, Edinburgh EH3 9YW, Midlothian, Scotland Univ Edinburgh Edinburgh Midlothian Scotland EH3 9YW Midlothian, Scotland
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 4, volume: 162, anno: 2000,
pagine: 1210 - 1214
SICI:
1073-449X(200010)162:4<1210:FASOIU>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
APNEA-HYPOPNEA SYNDROME; DAYTIME SLEEPINESS; CPAP TITRATION; FRAGMENTATION; PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Douglas, NJ Univ Edinburgh, Royal Infirm NHS Trust, Sleep Ctr, Lauriston Pl, EdinburghEH3 9YW, Midlothian, Scotland Univ Edinburgh Lauriston Pl Edinburgh Midlothian Scotland EH3 9YW
Citazione:
K. Rees et al., "Frequency and significance of increased upper airway resistance during sleep", AM J R CRIT, 162(4), 2000, pp. 1210-1214

Abstract

Previous studies have shown that episodes of inspiratory flow limitation can be clinically important. We have challenged the hypothesis that patientswith the "upper airway resistance syndrome" have more episodes of inspiratory flow limitation, associated with greater swings in pleural pressure andmore arousals from sleep than normal subjects. We thus studied eight symptomatic patients with UARS (ESS > 10, AHI < 15) and eight matched asymptomatic subjects. All had overnight polysomnography with recording of pleural pressure and airflow derived from nasal pressure. Events scored visually using nasal pressure were termed flow limitation events and those using both signals "resistive events. " The patients with UARS had no more episodes of flow limitation or resistive events than the controls. However, pleural pressure swings at resistive event termination were significantly more negative in the patient group (-15 [IQR 9-19]; -11 [8-12] cm H2O; p = 0.02) and the number of cortical arousals associated with resistive events was higher in the patients (median, 10 [5-75]; 3 [1-9]/h slept; p = 0.02). This study confirms that patients with UARS have periods of increased upper airway resistance associated with significant sleep fragmentation. However, resistive events are also common in normal subjects, although these are associated withless negative pleural pressure swings and fewer arousals. Thus, the clinical significance of resistive events needs to be interpreted with caution.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 08:42:13