Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Electrical remodeling of the atria associated with paroxysmal and chronic atrial flutter
Autore:
Sparks, PB; Jayaprakash, S; Vohra, JK; Kalman, JM;
Indirizzi:
Royal Melbourne Hosp, Dept Cardiol, Melbourne, Vic 3050, Australia Royal Melbourne Hosp Melbourne Vic Australia 3050 ne, Vic 3050, Australia Univ Melbourne, Dept Med, Melbourne, Vic, Australia Univ Melbourne Melbourne Vic Australia pt Med, Melbourne, Vic, Australia
Titolo Testata:
CIRCULATION
fascicolo: 15, volume: 102, anno: 2000,
pagine: 1807 - 1813
SICI:
0009-7322(20001010)102:15<1807:EROTAA>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADIOFREQUENCY CATHETER ABLATION; ELECTROPHYSIOLOGICAL CHARACTERISTICS; REFRACTORY PERIOD; FIBRILLATION; HUMANS; MECHANISM; INITIATION; CONVERSION; CONDUCTION; REENTRY;
Keywords:
ablation; fibrillation; atrial flutter; remodeling;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Kalman, JM Royal Melbourne Hosp, Dept Cardiol, Grattan St, Melbourne, Vic 3050, Australia Royal Melbourne Hosp Grattan St Melbourne Vic Australia 3050 ia
Citazione:
P.B. Sparks et al., "Electrical remodeling of the atria associated with paroxysmal and chronic atrial flutter", CIRCULATION, 102(15), 2000, pp. 1807-1813

Abstract

Background-Atrial electrical remodeling may be important for the initiation and perpetuation of atrial arrhythmias. Whether paroxysmal atrial flutter(AFL) and chronic AFL cause electrical remodeling of the atria has not been conclusively determined. Methods and Results-Before radiofrequency ablation of paroxysmal AFL, 15 patients in sinus rhythm were evaluated under autonomic blockade. Lateral right atrial (LRA) effective refractory periods (ERPs) at 600 and 450 ms weremeasured before and at 1-minute intervals for 10 minutes after spontaneousor pace termination of a 5- to 10-minute period of induced AFL, In 10 patients with chronic AFL, LRA, septal, and coronary sinus (CS) ERPs and corrected sinus node recovery times (cSNRTs) at 600 and 450 ms were measured under autonomic blockade 15 minutes, 30 minutes, and 3 weeks after termination of chronic AFL by ablation, In the paroxysmal AFL group, LRA ERPs decreasedby 18% at 600 ms and 12% at 450 ms (P<0.01) after induced AFL and recovered to baseline over approximate to 5 minutes. Atrial fibrillation developed during AFL in 3 patients and during ERP testing in 3 patients when refractoriness was at its nadir. In the chronic AFL group, LRA, septal, and CS ERPsat 3 weeks were significantly greater than at 15 and 30 minutes after termination of chronic AFL at both cycle lengths (P<0.01), Three weeks after ablation, cSNRT decreased 35% at 600 ms (P<0.05) and decreased 44% at 450 ms (P<0.05). Both ERPs and cSNRTs measured 15 and 30 minutes after ablation ofchronic AFL were not significantly different. Conclusions-Both paroxysmal AFL and chronic AFL cause reversible electrical remodeling of the atria but demonstrate different time courses of recovery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 21:42:00