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Titolo:
EVIDENCE THAT ENDOGENOUS CORTICOTROPIN-RELEASING FACTOR SUPPRESSES BEHAVIORAL-RESPONSES OF GUINEA-PIG PUPS TO BRIEF ISOLATION IN NOVEL SURROUNDINGS
Autore:
HENNESSY MB; MCINTURF SM; MAZZEI SJ;
Indirizzi:
WRIGHT STATE UNIV,DEPT PSYCHOL DAYTON OH 45435
Titolo Testata:
Developmental psychobiology
fascicolo: 1, volume: 31, anno: 1997,
pagine: 39 - 47
SICI:
0012-1630(1997)31:1<39:ETECFS>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
INFANT SQUIRREL-MONKEYS; MATERNAL SEPARATION; RAT PUPS; ULTRASONIC VOCALIZATIONS; CAVIA-PORCELLUS; MOTHER; ACTIVATION; ATTACHMENT; CORTISOL; CRF;
Keywords:
CORTICOTROPIN-RELEASING FACTOR; MATERNAL SEPARATION; ISOLATION; HYPOTHALAMIC-PITUITARY-ADRENAL; GUINEA PIG;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
M.B. Hennessy et al., "EVIDENCE THAT ENDOGENOUS CORTICOTROPIN-RELEASING FACTOR SUPPRESSES BEHAVIORAL-RESPONSES OF GUINEA-PIG PUPS TO BRIEF ISOLATION IN NOVEL SURROUNDINGS", Developmental psychobiology, 31(1), 1997, pp. 39-47

Abstract

Guinea pig pups were injected subcutaneously with a corticotropin-releasing factor antagonist (CRF12-41) or saline vehicle and then placed into a novel cage for 30 or 60 min. Isolated 20- to 26-day-old pups vocalized more and exhibited more locomotor activity when given 15 to 150 mu g of CRF12-41 than when given saline. The presence of the mother in the test cage prevented the antagonist fl om affecting behavior. The influence of the antagonist during isolation was not limited to guineapigs near weaning age: CRF12-41 increased levels of vocalizing in isolated, 4- to 6-day-old pups, though no changes were seen in locomotoractivity. Results support the hypothesis that endogenous corticotropin-releasing factor, perhaps acting at a peripheral binding site, suppresses the active behavioral response characteristic of pups during theearly phase of isolation in novel surroundings. (C) 1997 John Wiley &Sons, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 16:09:57