Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Increased fibrinolytic activity and body cavity coagula
Autore:
Yamamoto, Y; Wakabayashi, G; Ando, N; Aikawa, N; Kitajima, M;
Indirizzi:
Keio Univ, Sch Med, Dept Surg, Shinjuku Ku, Tokyo 1608582, Japan Keio Univ Tokyo Japan 1608582 pt Surg, Shinjuku Ku, Tokyo 1608582, Japan
Titolo Testata:
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY
fascicolo: 9, volume: 30, anno: 2000,
pagine: 778 - 784
SICI:
0941-1291(2000)30:9<778:IFAABC>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLUNT ABDOMINAL-TRAUMA; NONOPERATIVE MANAGEMENT; COMPUTED-TOMOGRAPHY; FIBRINOPEPTIDE-A; HEPATIC-TRAUMA; SPLENIC TRAUMA; HUMAN-BLOOD; INJURIES;
Keywords:
body cavity coagula; rebleeding; fibrinolytic activity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Yamamoto, Y Nerima Gen Hosp, Dept Surg, Nerima Ku, 2-41-1, Tokyo 1768530, Japan Nerima Gen Hosp 2-41-1 Tokyo Japan 1768530 kyo 1768530, Japan
Citazione:
Y. Yamamoto et al., "Increased fibrinolytic activity and body cavity coagula", SURG TODAY, 30(9), 2000, pp. 778-784

Abstract

When a large volume of coagulum remains in the body cavity after trauma orsurgery, secondary fibrinolysis occurs, which disturbs the hemostatic balance and results in rebleeding. To better understand this condition, we conducted a clinical study on patients with and without coagula and an experimental study on fibrinolytic activity in a rat model. The results of the clinical study showed that when coagula existed in the body cavity, the blood levels of the fibrin degradation products D-dimer and fibrinopeptide B beta(15-42) remained high compared with when subjects were under similar stress but without the presence of coagula. In the experimental studies, fibrinolytic activity of the omentum, measured by the fibrin plate method, was higher in rats with hemoperitoneum. This suggests that increased fibrinolytic activity may lead to rebleeding from the area of transient hemostasis when coagulum is present in the body cavity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/21 alle ore 16:16:35