Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Na-23 MRI for imaging of myocardial infarction in human
Autore:
Sandstede, J; Pabst, T; Beer, M; Harre, K; Baurle, K; Lipke, C; Butter, F; Kenn, W; Volker, W; Neubauer, S; Hahn, D;
Indirizzi:
Univ Wurzburg, Inst Rontgendiagnost, D-97080 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97080 agnost, D-97080 Wurzburg, Germany Univ Wurzburg, Med Klin, D-97080 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97080 d Klin, D-97080 Wurzburg, Germany Univ Oxford, John Radcliffe Hosp, Dept Cardiovasc Med, Oxford OX1 2JD, England Univ Oxford Oxford England OX1 2JD rdiovasc Med, Oxford OX1 2JD, England
Titolo Testata:
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
fascicolo: 9, volume: 172, anno: 2000,
pagine: 739 - 743
SICI:
1438-9029(200009)172:9<739:NMFIOM>2.0.ZU;2-H
Fonte:
ISI
Lingua:
GER
Soggetto:
CONTRAST AGENT; GD-DTPA; SIZE; SODIUM;
Keywords:
heart, MRI; myocardial infarction; sodium-MRI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Sandstede, J Univ Wurzburg, Inst Rontgendiagnost, Josef Schneider Str 2, D-97080 Wurzburg, Germany Univ Wurzburg Josef Schneider Str 2 Wurzburg Germany D-97080
Citazione:
J. Sandstede et al., "Na-23 MRI for imaging of myocardial infarction in human", ROFO-F RONT, 172(9), 2000, pp. 739-743

Abstract

Sodium is elevated in acute/subacute myocardial infarction due to three distinct mechanisms: Breakdown of ion homeostasis with accumulation of intracellular sodium, extracellular edema formation and, during scar formation, increase of extracellular vs, intracellular space as cardiomyocytes are replaced by connective tissue. Na-23 MRI has previously been shown to have the potential to demonstrate myocardial infarction in an animal model. Aim of this study was, therefore, to demonstrate myocardial infarction with the useof Na-23-MRI in patients. Material and Methods: 10 patients were examined 14+/-7 days after first myocardial infarction using a Na-23 surface coil at1.5 T. Double angulated short axis images of the entire heart were imaged using an EGG-triggered 3d-FLASH-sequence (FOV, 450 mm; matrix, 64 x 128; spatial resolution, 3.5 x 7 mm(2); slice thickness, 16 mm; 32 acquisitions). Areas of elevated sodium signal intensity were correlated with infarct-related wall motion abnormalities imaged by Cine MRI in breathhold-technique. Results: All patients showed an area of elevated sodium signal intensity that correlated well with the clinically determined localization of myocardialinfarction as well as with regional wall motion abnormalities detected by Cine MRI. Conclusions: Elevated Na-23 MR image signal intensity demonstrates subacute myocardial infarction in patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/10/20 alle ore 04:42:27