Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Subchronic hydrocortisone treatment alters auditory evoked potentials in normal subjects
Autore:
Ashton, CH; Lunn, B; Marsh, VR; Young, AH;
Indirizzi:
Univ Newcastle Upon Tyne, Royal Victoria Infirm, Sch Neurosci & Psychiat, Dept Psychiat, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England Univ Newcastle Upon Tyne Newcastle Upon Tyne Tyne & Wear England NE1 4LP
Titolo Testata:
PSYCHOPHARMACOLOGY
fascicolo: 1, volume: 152, anno: 2000,
pagine: 87 - 92
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVENT-RELATED POTENTIALS; CORTICOTROPIN-RELEASING HORMONE; ACTH 4-9 ANALOG; DECLARATIVE MEMORY; DEPRESSED-PATIENTS; MAJOR DEPRESSION; CORTISOL-LEVELS; SCHIZOPHRENIA; P300; RESPONSES;
Keywords:
hydrocortisone; normal volunteers; electroencephalogram (EEG); auditory evoked potential; P-300; background EEG frequencies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
47
Recensione:
Indirizzi per estratti:
Indirizzo: Young, AH Univ Newcastle Upon Tyne, Royal Victoria Infirm, Sch Neurosci & Psychiat, Dept Psychiat, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England Univ Newcastle Upon Tyne Newcastle Upon Tyne Tyne & Wear England NE1 4LP
Citazione:
C.H. Ashton et al., "Subchronic hydrocortisone treatment alters auditory evoked potentials in normal subjects", PSYCHOPHAR, 152(1), 2000, pp. 87-92

Abstract

Rationale: Abnormalities of cortical evoked potentials and background electroencephalographic (EEG) frequencies occur in several psychiatric disorders, some of which, especially depression, are associated with hypercortisolaemia. However, there have been few investigations of the effects of exogenously administered cortisol on waking EEG measures. Objectives: To examine the effects of subchronic hydrocortisone administration on auditory evoked potentials and background EEG activity. Methods: Hydrocortisone, 20 mg twicedaily, or placebo was administered to 30 normal male volunteers for 7 daysin a between-subjects, double-blind trial. Auditory evoked potentials and EEG frequencies were measured on the last day. Results: Hydrocortisone significantly increased the amplitudes of the N1P2 and P-300 components of the auditory evoked response, but there was no change in background EEG, Conclusion: The results indicate that subchronic hydrocortisone treatment in normal subjects increases the amplitude of auditory evoked potentials, possiblyreflecting a central alerting effect.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/02/20 alle ore 15:01:47