Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Paraneoplastic pemphigus with circulating antibodies directed exclusively against the pemphigus vulgaris antigen desmoglein 3
Autore:
Bouloc, A; Joly, P; Saint-Leger, E; Wechsler, J; Roujeau, JC; Revuz, J;
Indirizzi:
Hop Henri Mondor, Dept Dermatol, F-94010 Creteil, France Hop Henri MondorCreteil France F-94010 ermatol, F-94010 Creteil, France Hop Henri Mondor, Dept Pathol, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 Pathol, F-94010 Creteil, France Hop Charles Nicolle, Dept Dermatol, Rouen, France Hop Charles Nicolle Rouen France Nicolle, Dept Dermatol, Rouen, France Hop Charles Nicolle, INSERM U519, Rouen, France Hop Charles Nicolle Rouen France es Nicolle, INSERM U519, Rouen, France
Titolo Testata:
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
fascicolo: 4, volume: 43, anno: 2000,
pagine: 714 - 717
SICI:
0190-9622(200010)43:4<714:PPWCAD>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
EROSIVE LICHEN-PLANUS; INDIRECT IMMUNOFLUORESCENCE; DESMOSOMAL PLAQUE; IMMUNOBLOT; NEOPLASIA; FOLIACEUS; ERUPTION; DISEASE; PATIENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Bouloc, A Hop Henri Mondor, Dept Dermatol, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 -94010 Creteil, France
Citazione:
A. Bouloc et al., "Paraneoplastic pemphigus with circulating antibodies directed exclusively against the pemphigus vulgaris antigen desmoglein 3", J AM ACAD D, 43(4), 2000, pp. 714-717

Abstract

A patient with follicular B-cell lymphoma presented with erythroderma associated with cutaneous and mucosal blisters. Histologic and direct immunofluorescence analysis of lesional skin showed a typical pattern of paraneoplastic pemphigus (PNP). Interestingly, indirect immunofluorescence on rat bladder was negative and immunoblot analysis of the patient's serum on epidermal extracts demonstrated antiepidermal antibodies that only recognized the pemphigus vulgaris antigen desmoglein 3, with no antibodies directed againstthe different proteins of the plakin family To our knowledge this has never been reported in the literature. It exemplifies the overlap between pemphigus vulgaris and PNP and the pathogenic role of antidesmoglein 3 antibodies in PNP. Moreover, it underscores the need to consider clinical, histologic, and immunologic features fur the diagnosis of PNP.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 17:41:21