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Titolo:
Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy
Autore:
Vigna, E; Naldini, L;
Indirizzi:
Univ Turin, Sch Med, Inst Canc Res & Treatment, IRCC,Lab Gene Transfer & Therapy, I-1060 Turin, Italy Univ Turin Turin Italy I-1060 ne Transfer & Therapy, I-1060 Turin, Italy
Titolo Testata:
JOURNAL OF GENE MEDICINE
fascicolo: 5, volume: 2, anno: 2000,
pagine: 308 - 316
SICI:
1099-498X(200009/10)2:5<308:LVETFE>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNODEFICIENCY-VIRUS TYPE-1; MURINE LEUKEMIA-VIRUS; REV-INDEPENDENT EXPRESSION; HEMATOPOIETIC STEM-CELLS; NONDIVIDING CELLS; IN-VIVO; NUCLEAR EXPORT; HIV-1 INFECTION; EFFICIENT TRANSDUCTION; REVERSE TRANSCRIPTION;
Keywords:
gene transfer; gene therapy; lentiviral vector; HIV-derived vector; biosafety; non-primate lentiviral vectors;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
84
Recensione:
Indirizzi per estratti:
Indirizzo: Naldini, L Univ Turin, Sch Med, Inst Canc Res & Treatment, IRCC,Lab Gene Transfer & Therapy, Str Prov 142,Km 3-9, I-1060 Turin, Italy Univ Turin Str Prov 142,Km 3-9 Turin Italy I-1060 Turin, Italy
Citazione:
E. Vigna e L. Naldini, "Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy", J GENE MED, 2(5), 2000, pp. 308-316

Abstract

Lentiviral vectors are tools for gene transfer derived From lentiviruses. From their first application to now they have been strongly developed in design, in biosafety and in their ability of transgene expression into targetcells. Primate and non-primate derived lentiviral vectors are now available and with both types of systems a lot of studies tuned to improve their performances in a large number of tissues are ongoing. Here we review the state of the art of lentiviral Vector systems discussing their potential for gene therapy. Copyright (C) 2000 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 20:10:46