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Titolo:
HELICOBACTER-PYLORI REINFECTION IS VIRTUALLY ABSENT AFTER SUCCESSFUL ERADICATION
Autore:
VANDERHULST RWM; RAUWS EAJ; KOYCU B; KELLER JJ; TENKATE FJW; DANKER J; TYTGAT GNJ; VANDERENDE A;
Indirizzi:
UNIV AMSTERDAM,ACAD MED CTR,DEPT GASTROENTEROL,MEIBERGDREEF 9 NL-1105AZ AMSTERDAM NETHERLANDS UNIV AMSTERDAM,ACAD MED CTR,DEPT GASTROENTEROL,MED MICROBIOL & HISTOPATHOL NL-1105 AZ AMSTERDAM NETHERLANDS
Titolo Testata:
The Journal of infectious diseases
fascicolo: 1, volume: 176, anno: 1997,
pagine: 196 - 200
SICI:
0022-1899(1997)176:1<196:HRIVAA>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
DUODENAL-ULCER; CAMPYLOBACTER-PYLORI; TRIPLE THERAPY; INFECTION; RECURRENCE; RECRUDESCENCE; TRANSMISSION; DIAGNOSIS; DISEASE; TRIAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
R.W.M. Vanderhulst et al., "HELICOBACTER-PYLORI REINFECTION IS VIRTUALLY ABSENT AFTER SUCCESSFUL ERADICATION", The Journal of infectious diseases, 176(1), 1997, pp. 196-200

Abstract

This study examined whether reinfection or recrudescence accounts forthe reappearance of Helicobacter pylori infection after apparent successful eradication. In a prospective study, 173 patients cured from H.pylori infection underwent follow-up endoscopies, with biopsies for culture and histopathology, every 3 months during the first year after treatment. Subsequently, elective half-yearly endoscopies were performed in 124 patients; the remaining 49 underwent follow-up endoscopy only in 1995. At reappearing infection, DNA profiles of pretreatment and recurrent strains were compared. After 3.5 years (range, 1.0-9.2), H. pylori infection recurred in 4 patients (5.2%). Reappearing infectionswere classified as endoscopically transmitted reinfection (n = 2), unclassified because of loss of pretreatment isolate (n = 1), or recrudescence (identical DNA patterns before and after treatment; n = 6). Thereappearance rate of infection, discarding endoscopic transmission, was 1.2% (7/601 H. pylori-negative patient-years). There was virtually no reinfection with H. pylori after eradication in this adult Western population. These data do not rule out acquisition of H. pylori.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 07:09:03