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Titolo:
The neurobiology of attention-deficit hyperactivity disorder
Autore:
Himelstein, J; Schulz, KP; Newcorn, JH; Halperin, JM;
Indirizzi:
CUNY, Grad Ctr, Dept Psychol, Neuropsychol Doctoral Subprogram, New York, NY 10016 USA CUNY New York NY USA 10016 ol Doctoral Subprogram, New York, NY 10016 USA Mt Sinai Med Ctr, New York, NY 10029 USA Mt Sinai Med Ctr New York NY USA10029 ai Med Ctr, New York, NY 10029 USA CUNY Queens Coll, Dept Psychol, Flushing, NY 11367 USA CUNY Queens Coll Flushing NY USA 11367 pt Psychol, Flushing, NY 11367 USA
Titolo Testata:
FRONTIERS IN BIOSCIENCE
, volume: 5, anno: 2000,
pagine: D461 - D478
SICI:
1093-9946(20000401)5:<D461:TNOAHD>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORPUS-CALLOSUM MORPHOLOGY; CEREBRAL GLUCOSE-METABOLISM; FLUID MONOAMINE METABOLITES; ANTERIOR CINGULATE CORTEX; DOPAMINE TRANSPORTER GENE; MINIMAL BRAIN-DYSFUNCTION; LOCUS-COERULEUS NEURONS; MAGNETIC-RESONANCE; DEFICIT/HYPERACTIVITY DISORDER; SUSTAINED ATTENTION;
Keywords:
attention-deficit; hyperactivity disorder; neurobiology; executive functions; fronto-striatal circuitry; dopamine; norepinephrine; review;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
159
Recensione:
Indirizzi per estratti:
Indirizzo: Halperin, JM CUNY Queens Coll, Dept Psychol, 65-30 Kissena Blvd, Flushing,NY 11367 USA CUNY Queens Coll 65-30 Kissena Blvd Flushing NY USA 11367 USA
Citazione:
J. Himelstein et al., "The neurobiology of attention-deficit hyperactivity disorder", FRONT BIOSC, 5, 2000, pp. D461-D478

Abstract

Attention-deficit hyperactivity disorder is a childhood psychiatric disorder characterized by inattention, impulsivity, and overactivity. Considerable research has focused on the neurobiological substrates of this disorder. Although the specific nature of the brain dysfunction remains elusive, progress has been made and several models of the underlying pathophysiology have been suggested. Research in the fields of neuropsychology, neuroimaging, neurochemistry, and molecular genetics, which points to a multifactorial etiology for the disorder, is reviewed. While several inconsistencies exist across studies, evidence supports dysfunction of fronto-striatal dopaminergic and noradrenergic circuits with resultant executive deficits in cognitivefunctioning.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:22:52