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Titolo:
Left ventricular apical thrombus and myocardial viability: A dobutamine stress echocardiographic study
Autore:
Cusick, DA; Bonow, RO; Chaudhry, FA;
Indirizzi:
Northwestern Univ, Sch Med, Dept Med, Div Cardiol, Chicago, IL 60611 USA Northwestern Univ Chicago IL USA 60611 Div Cardiol, Chicago, IL 60611 USA
Titolo Testata:
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
fascicolo: 6, volume: 17, anno: 2000,
parte:, 1
pagine: 547 - 554
SICI:
0742-2822(200008)17:6<547:LVATAM>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; TWO-DIMENSIONAL ECHOCARDIOGRAPHY; LOW-DOSE DOBUTAMINE; DILATED CARDIOMYOPATHY; HIBERNATING MYOCARDIUM; REVERSIBLE DYSFUNCTION; THROMBOLYTIC THERAPY; INFARCTION; SURVIVAL; REVASCULARIZATION;
Keywords:
ventricular thrombus; myocardial viability; dobutamine stress echocardiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Chaudhry, FA St Lukes Roosevelt Hosp, 1111 Amsterdam Ave, New York, NY 10025 USA St Lukes Roosevelt Hosp 1111 Amsterdam Ave New York NY USA 10025
Citazione:
D.A. Cusick et al., "Left ventricular apical thrombus and myocardial viability: A dobutamine stress echocardiographic study", ECHOCARDIOG, 17(6), 2000, pp. 547-554

Abstract

The objective of this article was to determine whether the presence of left ventricular apical thrombus is a marker of nonviable myocardium. Reduced coronary blood flow secondary to atherosclerosis may result in chronic reversible left ventricular wall-motion abnormalities. Severe regional abnormalities also predispose to formation of left ventricular thrombus. The relationship between left ventricular apical thrombus and myocardial viability has not been previously described. Eighty patients with coronary artery disease and chronic left ventricular dysfunction were studied by dobutamine stress echocardiography. Left ventricular apical thrombus was identified using echocardiographic criteria. Wall-motion analysis was performed using a standard 16-segment model and ejection fraction was calculated As a result, 48 patients (60%) had definite or highly suspicious findings for left ventricular thrombus (group 1), and 32 patients (40%) had no thrombus (group 2). Group 1 had significantly higher composite (54.0 +/- 5.8 vs 43.3 +/- 6.4) andapical (6.0 +/- 2.7 vs 12.4 +/- 3.4) wall-motion scores compared to those in group 2 (P = 0.01). Thirty-two patients (67%) in group 1 demonstrated nocontractile reserve in the apical segments, consistent with lack of viability, versus eight patients (25%) in group 2 (P = 0.0003). The number of viable apical segments per patient was significantly less in group 1 (0.7 +/- 1.2) versus group 2 (1.8 +/- 1.3) (P = 0.01). Left ventricular apical thrombus is more likely to be present when, there is absence of myocardial viability in the corresponding segments.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 09:47:19