Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Improved survival after acute myocardial infarction in patients with advanced Killip class
Autore:
Miller, WL; Wright, RS; Grill, JP; Kopecky, SL;
Indirizzi:
Mayo Clin & Mayo Fdn, Div Cardiovasc Dis, CCU Grp, Dept Internal Med, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Rochester MN USA 55905 Med, Rochester, MN 55905 USA Mayo Clin Phys Alliance Clin Trials, Rochester, MN USA Mayo Clin Phys Alliance Clin Trials Rochester MN USA , Rochester, MN USA
Titolo Testata:
CLINICAL CARDIOLOGY
fascicolo: 10, volume: 23, anno: 2000,
pagine: 751 - 758
SICI:
0160-9289(200010)23:10<751:ISAAMI>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR EJECTION FRACTION; GUSTO-I TRIAL; CARDIOGENIC-SHOCK; RISK STRATIFICATION; EARLY REVASCULARIZATION; CORONARY ANGIOPLASTY; REPERFUSION THERAPY; GLOBAL UTILIZATION; PROGNOSTIC VALUE; HEART-FAILURE;
Keywords:
acute myocardial infarction; Killip class; reperfusion therapy; in-hospital mortality; long-term mortality;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Miller, WL Mayo Clin & Mayo Fdn, Div Cardiovasc Dis, CCU Grp, Dept Internal Med, MayoBldg,E 16 B,200 1st St SW, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Mayo Bldg,E 16 B,200 1st St SW Rochester MN USA 55905
Citazione:
W.L. Miller et al., "Improved survival after acute myocardial infarction in patients with advanced Killip class", CLIN CARD, 23(10), 2000, pp. 751-758

Abstract

Background: The continuing applicability of the Killip classification system to the effective stratification of longterm and short-term outcome in patients with acute myocardial infarction (MI) and its influence on treatmentstrategy calls for reanalysis in the setting of today's primary reperfusion treatments. Hypothesis: Our study sought to test the hypothesis that Killip classification, established on admission in patients with acute MI, is an effective tool for early prediction of in-hospital mortality and long-term survival. Methods: A series of 909 consecutive Olmsted County patients admitted withacute MI to St. Marys Hospital, Mayo Clinic, between January 1988 and March 1998 was analyzed. Killip classification was the primary variable. Endpoints were in-hospital death, major in-hospital complications, and posthospital death. Results: Patients analyzed included 714 classified as Killip I, 170 classified as Killip II/III, and 25 classified as Killip TV. Increases in in-hospital mortality and prevalence of in-hospital complications correspond significantly with advanced Killip class (p < 0.01), with in-hospital mortality 7% in class I, 17.6% in classes II/III, and 36% in class TV patients (p < 0.001). Killip classification was strongly associated with mode of therapy administered within 24 h of admission (p < 0.01). Killip TV patients underwent primary angioplasty most commonly and were less likely to receive medical therapy. Conclusions: Killip classification remains a strong independent predictor of in-hospital mortality and complications, and of long-term survival. Early primary angioplasty has contributed to a decrease in mortality in Killip IV patients, but effective adjunctive medical therapy is underutilized.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:50:54