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Titolo:
Incidence of the preconceptional management of type 1 diabetes on the outcome of pregnancy
Autore:
Jaffiol, C; Baccara, MT; Renard, E; Apostol, DJ; Lefebvre, P; Boulot, P; Daures, JP; Bringer, J;
Indirizzi:
Hop Lapeyronie, Serv Endocrinol, F-34295 Montpellier 5, France Hop Lapeyronie Montpellier France 5 rinol, F-34295 Montpellier 5, France
Titolo Testata:
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE
fascicolo: 5, volume: 184, anno: 2000,
pagine: 995 - 1008
SICI:
0001-4079(2000)184:5<995:IOTPMO>2.0.ZU;2-T
Fonte:
ISI
Lingua:
FRE
Soggetto:
INTRAPERITONEAL INSULIN INFUSION; CONGENITAL-ANOMALIES; SPONTANEOUS-ABORTION; WOMEN; MELLITUS; HEMOGLOBIN-A1C; MALFORMATION; RETINOPATHY; EXPERIENCE; INFANTS;
Keywords:
diabete mellitus; insulin-dependant, epidemiology; pregnancy in diabetes; abnormalities; hemoglobine A, glycosylated; fetal death;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Jaffiol, C Hop Lapeyronie, Serv Endocrinol, F-34295 Montpellier 5, France Hop Lapeyronie Montpellier France 5 295 Montpellier 5, France
Citazione:
C. Jaffiol et al., "Incidence of the preconceptional management of type 1 diabetes on the outcome of pregnancy", B ACA N MED, 184(5), 2000, pp. 995-1008

Abstract

Foetal mortality and morbidity remain dramaticaly increased in diabetic women. To evaluate the benefit of a preconceptional education combined with agood metabolic control, we compared the outcome of pregnancy in 2 groups of type I diabetic women: group A (n=21) planned before conception versus group B (n=40) not planned. Both groups were similar related to the type and duration of diabetes, its complications, age, body mass index and differentfactors of risk. In group A, HbA1C levels were less than or equal to 3 SD of the normal mean of non diabetic values before conception and during the pregnancy course and greater than or equal to 3 SD in group B. We observed a significant reduction (p<0.05) of the main adverse events regarding foetus outcome (foetal, perinatal and neonatal mortality, malformations) and obstetrical complications in the planned group. These data lead to the need ofan extensive policy of early planification of pregnancy in diabetic women.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 16:32:43