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Titolo:
Neural and behavioral teratological evaluation of rats exposed to ultra-wideband electromagnetic fields
Autore:
Cobb, BL; Jauchem, JR; Mason, PA; Dooley, MP; Miller, SA; Ziriax, JM; Murphy, MR;
Indirizzi:
USAF, Res Lab, HEDR,Human Effectiveness Directorate, Directed Energy Bioeffects Div,Radio Frequency Ra, Brooks AFB, TX 78235 USA USAF Brooks AFB TX USA 78235 Radio Frequency Ra, Brooks AFB, TX 78235 USA Veridian Engn Inc, San Antonio, TX USA Veridian Engn Inc San Antonio TX USA idian Engn Inc, San Antonio, TX USA Iowa State Univ, Dept Biomed Sci, Coll Vet Med, Ames, IA USA Iowa State Univ Ames IA USA Dept Biomed Sci, Coll Vet Med, Ames, IA USA USAF, Hlth Res Ctr Detachment, Brooks AFB, TX 78235 USA USAF Brooks AFB TX USA 78235 Res Ctr Detachment, Brooks AFB, TX 78235 USA
Titolo Testata:
BIOELECTROMAGNETICS
fascicolo: 7, volume: 21, anno: 2000,
pagine: 524 - 537
SICI:
0197-8462(200010)21:7<524:NABTEO>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEAD-EXPOSURE; MICROWAVE-RADIATION; BLOOD-PRESSURE; HEART-RATE; PULSES;
Keywords:
electromagnetic fields; teratology; high peak power pulses; behavior;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Cobb, BL USAF, Res Lab, HEDR,Human Effectiveness Directorate, Directed Energy Bioeffects Div,Radio Frequency Ra, Bldg 1162,8315 Hawks Rd, Brooks AFB,TX 78235USA USAF Bldg 1162,8315 Hawks Rd Brooks AFB TX USA 78235 TX 78235USA
Citazione:
B.L. Cobb et al., "Neural and behavioral teratological evaluation of rats exposed to ultra-wideband electromagnetic fields", BIOELECTROM, 21(7), 2000, pp. 524-537

Abstract

Several investigators have reported teratologic effects of electromagneticfield exposure. The majority of these studies have been performed at levels of exposure that could produce substantial heating of the animals. New and unique sources of ultra-wideband (UWB) electromagnetic fields are currently being developed and tested that are capable of generating nonthermalizing, high-peak-power, microwave (MW) pulses with nanosecond (ns) pulse widths, picosecond tps) rise times, and an UWB of frequencies. Our study was performed to determine if teratological changes occur in rat pups as a result of (i) daily UWB exposures during gestation days 3-18, or (ii) as a result of both prenatal and postnatal (10 days) exposures. Dams were exposed eitherto (i) UWB irradiation from a Kentech system that emitted a 55 kV/m-peak Efield, 300 ps rise time, and a 1.8 ns pulse width, average whole-body specific absorption rate 45 mW/kg; (ii) sham irradiation; or (iii) a positive control, lead (Pb) acetate solution (2000 mu g/ml) continuously available inthe drinking water. Offspring were examined for ontogeny (litter size, sex-ratios, weights, coat appearance, tooth-eruption, eye-opening, air-righting, and ultrasonic stress vocalizations). Male pups were tested on various performance measures (locomotor, water-maze learning, and fertilization capabilities). The pups postnatally exposed were examined for hippocampal morphology and operant behavior. Behavioral, functional, and morphological effects of UWB exposure were unremarkable with these exceptions: (i) The UWB-exposed pups emitted significantly more stress vocalizations than the sham-exposed pups; (ii) the medial-to-lateral length of the hippocampus was significantly longer in the UWB-exposed pups than in the sham-exposed animals; (iii) male offspring exposed in utero to UWB mated significantly less frequently than sham-exposed males, but when they did mate there was no difference in fertilization and offspring numbers from the sham group. There does not appear to be a unifying physiological or behavioral relationship among the significant differences observed, and our findings could be due to the expected spurious results derived when a large number of statistical comparisons are made. Significant effects found between our positive-controls and other groups on numerous measures indicates that the techniques used were sensitive enough to detect teratological effects. Published 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 20:42:54