Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Systematic review of the cost effectiveness of prophylactic treatments in the prevention of gastropathy in patients with rheumatoid arthritis or osteoarthritis taking non-steroidal anti-inflammatory drugs
Autore:
van Dieten, HEM; Korthals-de Bos, IBC; van Tulder, MW; Lems, WF; Dijkmans, BAC; Boers, M;
Indirizzi:
Free Univ Amsterdam, Dept Clin Epidemiol & Biostat, NL-1081 BT Amsterdam, Netherlands Free Univ Amsterdam Amsterdam Netherlands NL-1081 BT terdam, Netherlands Free Univ Amsterdam, Dept Rheumatol, NL-1081 BT Amsterdam, Netherlands Free Univ Amsterdam Amsterdam Netherlands NL-1081 BT terdam, Netherlands
Titolo Testata:
ANNALS OF THE RHEUMATIC DISEASES
fascicolo: 10, volume: 59, anno: 2000,
pagine: 753 - 759
SICI:
0003-4967(200010)59:10<753:SROTCE>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; INDUCED GASTRIC-ULCER; PLACEBO-CONTROLLED TRIAL; ECONOMIC-EVALUATION; GASTROINTESTINAL TOXICITY; MISOPROSTOL PROPHYLAXIS; DOUBLE-BLIND; GUIDELINES; NSAIDS; EVENTS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: van Dieten, HEM Free Univ Amsterdam, Dept Clin Epidemiol & Biostat, Boechorststr 7, NL-1081 BT Amsterdam, Netherlands Free Univ Amsterdam Boechorststr 7 Amsterdam Netherlands NL-1081 BT
Citazione:
H.E.M. van Dieten et al., "Systematic review of the cost effectiveness of prophylactic treatments in the prevention of gastropathy in patients with rheumatoid arthritis or osteoarthritis taking non-steroidal anti-inflammatory drugs", ANN RHEUM D, 59(10), 2000, pp. 753-759

Abstract

A systematic review on the cost effectiveness of prophylactic treatments of nonsteroidal anti-inflammatory drug (NSAID) induced gastropathy in patients with osteoarthritis or rheumatoid arthritis was conducted. Two reviewersconducted the literature search and the review. Both full and partial economic evaluations published in English, Dutch, or German were included. The criteria list published in the textbook of Drummond was used to determine the quality of the economic evaluations. The methodological quality of threerandomised controlled trials (RCTs) in which the economic evaluations obtained probability estimates of NSAID induced gastropathy and adverse events was assessed by a list of internal validity criteria. The conclusions were based on a rating system consisting of four levels of evidence. Ten economic evaluations were included; three were based on RCTs. All evaluations studied misoprostol as prophylactic treatment: in one evaluation misoprostol was studied as a fixed component in a combination with diclofenac(Arthrotec). All economic evaluations comprised analytical studies containing a decision tree. The three trials were of high methodological quality. Nine economic evaluations were considered high quality and one economic evaluation was considered of low methodological quality. There is strong evidence (level "A") that the use of misoprostol for the prevention of NSAID induced gastropathy is cost effective, and limited evidence (level "C") that the use of Arthrotec is cost effective. Although the levels of evidence usedin this review are arbitrary, it is believed that a qualitative analysis is useful: quantitative analyses in this field are hampered by the heterogeneity of economic evaluations. Existing criteria to evaluate the methodological quality of economic evaluations may need refinement for use in systematic reviews.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/05/20 alle ore 13:27:54