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Titolo:
Pavlovian conditioning of taste aversion using a motion sickness paradigm
Autore:
Klosterhalfen, S; Ruttgers, A; Krumrey, E; Otto, B; Stockhorst, U; Riepl, RL; Probst, T; Enck, P;
Indirizzi:
Univ Munich, Dept Internal Med, Munich, Germany Univ Munich Munich Germany v Munich, Dept Internal Med, Munich, Germany Univ Tubingen, Tubingen, Germany Univ Tubingen Tubingen GermanyUniv Tubingen, Tubingen, Germany Univ Dusseldorf, Inst Med Psychol, D-4000 Dusseldorf, Germany Univ Dusseldorf Dusseldorf Germany D-4000 ol, D-4000 Dusseldorf, Germany Univ Dusseldorf, Inst Psychol, D-4000 Dusseldorf, Germany Univ DusseldorfDusseldorf Germany D-4000 ol, D-4000 Dusseldorf, Germany
Titolo Testata:
PSYCHOSOMATIC MEDICINE
fascicolo: 5, volume: 62, anno: 2000,
pagine: 671 - 677
SICI:
0033-3174(200009/10)62:5<671:PCOTAU>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
CANCER-CHEMOTHERAPY; NAUSEA; HUMANS; PROFILES;
Keywords:
Pavlovian conditioning; taste aversion; motion sickness; nausea;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Enck, P Zentrum Med Forsch, Waldhornle Str 22, D-72072 Tubingen, Germany Zentrum Med Forsch Waldhornle Str 22 Tubingen Germany D-72072 any
Citazione:
S. Klosterhalfen et al., "Pavlovian conditioning of taste aversion using a motion sickness paradigm", PSYCHOS MED, 62(5), 2000, pp. 671-677

Abstract

Objective: Pavlovian conditioning of taste aversion has rarely been investigated in healthy humans using motion sickness as the unconditioned stimulus (US). Methods: Ninety subjects were pretested for susceptibility to illusory motion (vection) in a rotating drum. Thirty-two subjects susceptible topseudomotion were assigned randomly to two groups and received either water 1 hour before rotation and a novel taste (elderberry juice, conditioned stimulus, [CS]) immediately before rotation in a rotating chair (conditioning group), of the sequence of water and juice was reversed (control group). During the test session 1 week later, all subjects were exposed to water 1 hour before and juice immediately before rotation. The amount of liquids ingested, nausea ratings, rotation tolerance, and blood levels of hormones (ACTH, ADH, PP) were evaluated. Results: Subjects in the conditioning group developed taste aversion toward the novel taste, but not subjects in the control group. Postrotation nausea rating was affected marginally by conditioning, but rotation tolerance was not changed by conditioning. ACTH and ADH but not PP levels increased with rotation, but were unaffected by conditioning. Conclusions: Pavlovian conditioning of behavioral, but not of endocrine, indicators was effective in susceptible subjects using a rotating chair as US and a single CS-US pairing.

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Documento generato il 29/11/20 alle ore 03:27:43