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Titolo:
Hypocholesterolemic effect of soymilk supplementation with usual diet in premenopausal normolipidemic Japanese women
Autore:
Takatsuka, N; Nagata, C; Kurisu, Y; Inaba, S; Kawakami, N; Shimizu, H;
Indirizzi:
Gifu Univ, Sch Med, Dept Publ Hlth, Gifu 5008705, Japan Gifu Univ Gifu Japan 5008705 ch Med, Dept Publ Hlth, Gifu 5008705, Japan
Titolo Testata:
PREVENTIVE MEDICINE
fascicolo: 4, volume: 31, anno: 2000,
pagine: 308 - 314
SICI:
0091-7435(200010)31:4<308:HEOSSW>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEALTHY-YOUNG-WOMEN; SOY PROTEIN ISOLATE; PLASMA-LIPOPROTEINS; SERUM-LIPIDS; SOYBEAN PROTEIN; DAIRY PROTEIN; CHOLESTEROL; CASEIN; PRODUCTS; ISOFLAVONES;
Keywords:
soymilk; soy protein; normolipidemic; humans; intervention studies; cholesterol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Takatsuka, N Gifu Univ, Sch Med, Dept Publ Hlth, 40 Tsukasa Machi, Gifu 5008705, Japan Gifu Univ 40 Tsukasa Machi Gifu Japan 5008705 5008705, Japan
Citazione:
N. Takatsuka et al., "Hypocholesterolemic effect of soymilk supplementation with usual diet in premenopausal normolipidemic Japanese women", PREV MED, 31(4), 2000, pp. 308-314

Abstract

Background. The hypocholesterolemic effect of soy protein concentrates on normolipidemic subjects still remains unclear. Our objective is to assess the effect of soymilk supplementation, a whole soy product, with usual diet on serum lipids in normolipidemic subjects. Methods. We conducted a randomized controlled trial on 60 premenopausal normolipidemic Japanese women. After excluding 8 subjects whose initial serumconcentration of total cholesterol or triacyiglycerol was higher than 220 mg/dL (5.69 mmol/L) or 160 mg/dL (1.81 mmol/L), respectively, we encouragedthe subjects in the soymilk-supplemented group (n = 27) to consume 400 mt (408 g) of commercial regular soymilk daily during two menstrual cycles. There were no significant differences in variables, including nutrient intake, between the soymilk-supplemented and control (n = 25) groups before the intervention. Results. After the trial, we observed a significant decrease of 10.9 mg/dL, or 5.3%, in serum concentration of total cholesterol in the soymilk-supplemented group. During the intervention, nutrient intake assessment showed significant increases in nutrient densities of vitamin E, polyunsaturated fatty acids, isoflavones, and P/S ratio and decreases in total energy and nutrient densities of vitamin C and green tea in this group. A statistically significant decrease in serum total cholesterol could still be observed evenafter excluding the estimated hypocholesterolemic effects of soymilk's polyunsaturated fatty acids. Conclusions. Our results suggest the hypocholesterolemic effect of soymilk, a traditional whole soy product, in Asian countries in normolipidemic subjects. (C) 2000 American Health Foundation and Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 09:41:09