Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Suppression of transient 40-Hz auditory response by haloperidol suggests modulation of human selective attention by dopamine D-2 receptors
Autore:
Ahveninen, J; Kahkonen, S; Tiitinen, H; Pekkonen, E; Huttunen, J; Kaakkola, S; Ilmoniemi, RJ; Jaaskelainen, IP;
Indirizzi:
Univ Helsinki, Dept Psychol, Cognit Brain Res Unit, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 it, FIN-00014 Helsinki, Finland Univ Helsinki, Dept Neurol, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 ol, FIN-00014 Helsinki, Finland Univ Helsinki, Cent Hosp, Med Engn Ctr, BioMag Lab,Hosp Dist Helsinki & Uusimaa, Helsinki, Finland Univ Helsinki Helsinki Finland st Helsinki & Uusimaa, Helsinki, Finland Univ Helsinki, Cent Hosp, Dept Psychiat, Hosp Dist Helsinki & Uusimaa, Helsinki, Finland Univ Helsinki Helsinki Finland st Helsinki & Uusimaa, Helsinki, Finland Harvard Univ, Massachusetts Gen Hosp, Sch Med, NMR Ctr, Charlestown, MA USA Harvard Univ Charlestown MA USA p, Sch Med, NMR Ctr, Charlestown, MA USA
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 1, volume: 292, anno: 2000,
pagine: 29 - 32
SICI:
0304-3940(20000929)292:1<29:SOT4AR>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTEX;
Keywords:
40-Hz response; auditory; D-2 receptors; dopamine; event-related potentials; magnetoencephalography; electroencephalography; haloperidol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Ahveninen, J Univ Helsinki, Dept Psychol, Cognit Brain Res Unit, POB 13, FIN-00014 Helsinki, Finland Univ Helsinki POB 13 Helsinki Finland FIN-00014nki, Finland
Citazione:
J. Ahveninen et al., "Suppression of transient 40-Hz auditory response by haloperidol suggests modulation of human selective attention by dopamine D-2 receptors", NEUROSCI L, 292(1), 2000, pp. 29-32

Abstract

Cognitive processes including selective attention may depend on synchronous activity of neurons at the gamma-band (around 40 Hz). To determine the effect of neuroleptic challenge on transient auditory evoked 40-Hz response, simultaneous measurement of 122-channel magnetoencephalogram (MEG) and 64-channel electroencephalogram (EEG) was used. Either 2 mg of dopamine D-2-receptor antagonist haloperidol or a placebo was administered orally to 11 healthy subjects in a double-blind randomized crossover design in two separatesessions. The subjects attended to tones presented to one ear and ignored those presented to the other ear. Haloperidol significantly suppressed the transient 40-Hz electric response to the attended stimuli, while no significant effect was observed in the electric responses to the unattended tones or in the magnetic responses. The present result suggests that dopamine Dp receptors modulate selective attention. (C) 2000 Published by Elsevier Science Ireland ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:16:55