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Titolo:
Quality of life, epilepsy advances, and the evolving role of anticonvulsants in women with epilepsy
Autore:
Yerby, MS;
Indirizzi:
N Pacific Epilepsy Res, Portland, OR 97210 USA N Pacific Epilepsy Res Portland OR USA 97210 Res, Portland, OR 97210 USA Oregon Hlth Sci Univ, Dept Neurol Publ Hlth & Prevent Med, Portland, OR 97201 USA Oregon Hlth Sci Univ Portland OR USA 97201 nt Med, Portland, OR 97201 USA Oregon Hlth Sci Univ, Dept Obstet & Gynecol, Portland, OR 97201 USA OregonHlth Sci Univ Portland OR USA 97201 ynecol, Portland, OR 97201 USA
Titolo Testata:
NEUROLOGY
fascicolo: 5, volume: 55, anno: 2000, supplemento:, 1
pagine: S21 - S31
SICI:
0028-3878(200009)55:5<S21:QOLEAA>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURAL-TUBE DEFECTS; REPRODUCTIVE ENDOCRINE DISORDERS; COLLABORATIVE STUDY-GROUP; PLASMA-PROTEIN BINDING; CATAMENIAL EPILEPSY; ANTIEPILEPTIC DRUGS; MEDROXYPROGESTERONE ACETATE; VITAMIN SUPPLEMENTATION; PROGESTERONE THERAPY; MENSTRUAL DISORDERS;
Keywords:
antiepileptic drug; women; pregnancy;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
109
Recensione:
Indirizzi per estratti:
Indirizzo: Yerby, MS N Pacific Epilepsy Res, 2455 NW Marshall St,Suite 14, Portland, OR 97210 USA N Pacific Epilepsy Res 2455 NW Marshall St,Suite 14 Portland OR USA 97210
Citazione:
M.S. Yerby, "Quality of life, epilepsy advances, and the evolving role of anticonvulsants in women with epilepsy", NEUROLOGY, 55(5), 2000, pp. S21-S31

Abstract

In the United States, approximately 1.1 million women of childbearing age have epilepsy. Even though antiepileptic drugs (AEDs) control the seizures of about 80% of patients with epilepsy, the management of women with epilepsy (WWE) presents physicians with unique problems, ranging from the cosmetic consequences of some AEDs (e.g., changes in weight) to the seizures of catamenial epilepsy (apparently related to a relative lack of progesterone during the luteal phase of the menstrual cycle). In addition, the effectiveness of hormonal contraceptives can be reduced by enzyme-inducing AEDs. The pregnancies of WWE present a greater risk for complications: one-quarter to one-third of WWE experience an increase in seizure frequency. In addition, difficulties during labor and adverse outcomes (e.g., fetal mortality and malformations, neonatal hemorrhage, low birth weight, and developmental delay) are more likely. The practitioner must choose a course that both prevents seizures and minimizes fetal exposure to AEDs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 02:40:22