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Titolo:
DYSTONIC REACTION ASSOCIATED WITH DEXTROMETHORPHAN INGESTION IN A TODDLER
Autore:
WARDEN CR; DIEKEMA DS; ROBERTSON WO;
Indirizzi:
CHILDRENS HOSP & MED CTR,EMERGENCY SERV,MAILSTOP CH-04,4800 SAND POINT WAY NE SEATTLE WA 98105 UNIV WASHINGTON,SCH MED,DEPT PEDIAT SEATTLE WA 98195
Titolo Testata:
Pediatric emergency care
fascicolo: 3, volume: 13, anno: 1997,
pagine: 214 - 215
SICI:
0749-5161(1997)13:3<214:DRAWDI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Keywords:
DEXTROMETHORPHAN; ACUTE DYSTONIC REACTION; OPISTHOTONOS; EXTRAPYRAMIDAL SYMPTOMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
C.R. Warden et al., "DYSTONIC REACTION ASSOCIATED WITH DEXTROMETHORPHAN INGESTION IN A TODDLER", Pediatric emergency care, 13(3), 1997, pp. 214-215

Abstract

Introduction: Accidental ingestions of cough and cold preparations containing dextromethorphan (DM) are common in the toddler age group andrarely have serious consequences, Even large intentional overdoses byadults seldom lead to serious morbidity, There have been no previous reports of an extrapyramidal reaction due to a DM ingestion. Case report: We report a 30-month-old girl who ingested approximately 38 mg/kg dextromethorphan. She presented with opisthotonus, ataxia, and bidirectional nystagmus. There was no change in her status with the administration of naloxone, The child was given diphenhydramine with clearing of her opisthotonus but persistence of her ataxia and nystagmus. Discussion: A moderate ingestion of dextromethorphan in a toddler resulted in extrapyramidal symptoms with opisthotonus that responded to diphenhydramine, Dextromethorphan is known to have complex CNS effects and, insufficient doses, may have dopamine receptor blocking activity resulting in this dystonic reaction.

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Documento generato il 19/01/20 alle ore 00:26:21