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Titolo:
Dietary glycemic index in relation to metabolic risk factors and incidenceof coronary heart disease: the Zutphen Elderly Study
Autore:
van Dam, RM; Visscher, AWJ; Feskens, EJM; Verhoef, P; Kromhout, D;
Indirizzi:
Natl Inst Publ Hlth & Environm, Dept Chron Dis Epidemiol, NL-3720 BA Bilthoven, Netherlands Natl Inst Publ Hlth & Environm Bilthoven Netherlands NL-3720 BA herlands Univ Wageningen & Res Ctr, Div Human Nutr & Epidemiol, Wageningen, Netherlands Univ Wageningen & Res Ctr Wageningen Netherlands ageningen, Netherlands Wageningen Ctr Food Sci, Wageningen, Netherlands Wageningen Ctr Food Sci Wageningen Netherlands Wageningen, Netherlands Natl Inst Publ Hlth & Environm, Div Publ Hlth Res, NL-3720 BA Bilthoven, Netherlands Natl Inst Publ Hlth & Environm Bilthoven Netherlands NL-3720 BA herlands
Titolo Testata:
EUROPEAN JOURNAL OF CLINICAL NUTRITION
fascicolo: 9, volume: 54, anno: 2000,
pagine: 726 - 731
SICI:
0954-3007(200009)54:9<726:DGIIRT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPENDENT DIABETES-MELLITUS; TOTAL-ENERGY-INTAKE; GLUCOSE-TOLERANCE; INSULIN SENSITIVITY; CHOLESTEROL; MEN; ATHEROSCLEROSIS; DETERMINANTS; WOMEN; FIBER;
Keywords:
glycemic index; dietary-carbohydrates; elderly; coronary disease; myocardial infarction; dyslipidemia; hyperinsulinemia; hyperglycemia; epidemiology; prospective studies; cohort studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: van Dam, RM Natl Inst Publ Hlth & Environm, Dept Chron Dis Epidemiol, POB 1, NL-3720 BA Bilthoven, Netherlands Natl Inst Publ Hlth & Environm POB 1 Bilthoven Netherlands NL-3720 BA
Citazione:
R.M. van Dam et al., "Dietary glycemic index in relation to metabolic risk factors and incidenceof coronary heart disease: the Zutphen Elderly Study", EUR J CL N, 54(9), 2000, pp. 726-731

Abstract

Objective: To examine whether a high dietary glycemic index is associated with hyperinsulinemia, hyperglycemia, dyslipidemia and coronary heart disease (CHD) risk in elderly men. Design: Prospective study of incidence of major CHD (non-fatal myocardial infarction or death due to CHD) between 1985 and 1995 in 646 men, and a cross-sectional analysis of metabolic risk factors in 1990 in 394 men. Setting: Population based study in the Dutch town Zutphen. Subjects: Men aged 64-84y in 1985 without a history of CHD or diabetes, whose diet was assessed with the cross-check dietary history method. Results: The dietary glycemic index was positively correlated with consumption (g carbohydrate) of wheat bread (r = 0.47) and sugar products (r = 0.41) and inversely with fruit (r = -0.37) and milk (r = -0.40) consumption. During 4527 person-years of follow-up, 94 cases of CHD were documented. The risk ratio for CHD was 1.11 (95% CI, 0.66 - 1.87) for the highest as compared to the lowest tertile of glycemic index after correction for age, body mass index, physical activity, cigarette smoking, and dietary factors (P (trend) = 0.70). Furthermore, the glycemic index was not appreciably associated with blood concentrations of total cholesterol, HDL-cholesterol, triacylglycerols or (fasting or postload) insulin or glucose. Conclusions: Our findings do not support the hypothesis that a high-glycemic-index diet unfavorably affects metabolic risk factors or increases risk for CHD in elderly men without a history of diabetes or CHD.

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Documento generato il 30/03/20 alle ore 20:00:09