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Titolo:
Influenza vaccination and the risk of primary cardiac arrest
Autore:
Siscovick, DS; Raghunathan, TE; Lin, DY; Weinmann, S; Arbogast, P; Lemaitre, RN; Psaty, BM; Alexander, R; Cobb, LA;
Indirizzi:
Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA 98101 USAUniv Washington Seattle WA USA 98101 Hlth Res Unit, Seattle, WA 98101 USA Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 ept Epidemiol, Seattle, WA 98195 USA Univ Michigan, Inst Social Res, Ann Arbor, MI USA Univ Michigan Ann ArborMI USA higan, Inst Social Res, Ann Arbor, MI USA Univ Washington, Dept Biostat, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Dept Biostat, Seattle, WA 98195 USA Seattle King Cty Dept Publ Hlth, Seattle, WA USA Seattle King Cty Dept Publ Hlth Seattle WA USA ubl Hlth, Seattle, WA USA
Titolo Testata:
AMERICAN JOURNAL OF EPIDEMIOLOGY
fascicolo: 7, volume: 152, anno: 2000,
pagine: 674 - 677
SICI:
0002-9262(20001001)152:7<674:IVATRO>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
MYOCARDIAL-INFARCTION; EXCESS MORTALITY; ELDERLY PERSONS; EPIDEMICS; EFFICACY;
Keywords:
cardiac arrest; influenza; vaccination;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Siscovick, DS Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, 1730 Minor Ave,Suite 1360, Seattle, WA 98101 USA Univ Washington 1730 Minor Ave,Suite 1360 Seattle WA USA 98101
Citazione:
D.S. Siscovick et al., "Influenza vaccination and the risk of primary cardiac arrest", AM J EPIDEM, 152(7), 2000, pp. 674-677

Abstract

Influenza epidemics are associated with an excess of mortality not only from respiratory diseases but also from other causes, and cardiovascular mortality increases abruptly during influenza epidemics, with little evidence of a lag period. In a population-based case-control study, the authors examined whether influenza vaccination was associated with a reduced risk of out-of-hospital primary cardiac arrest (PCA), a major contributor to cardiovascular mortality in the community. Cases of PCA (n = 342) without prior heart disease or life-threatening comorbidity that occurred in King County, Washington, were identified from paramedic incident reports from October 1988 to July 1994. Demographically similar controls (n = 549) were identified from the community by using random digit dialing. Spouses of subjects were interviewed to assess treatment with influenza vaccine during the previous year and other risk factors. After adjustment for demographic, clinical, and behavioral risk factors, influenza vaccination was associated with a reduced risk of PCA (odds ratio = 0.51, 95 percent confidence interval: 0.33, 0.79). The authors suggest that while the association of influenza vaccinationwith a reduced risk of PCA is consistent with cohort studies of influenza vaccination and total mortality, further studies are needed to determine whether the observed association reflects protection or selection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 12:40:17