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Titolo:
Nonpalpable breast lesions: Evaluation with power Doppler US and a microbubble contrast agent - Initial experience
Autore:
Moon, WK; Im, JG; Noh, DY; Han, MC;
Indirizzi:
Seoul Natl Univ Hosp, Clin Res Inst, Seoul 110744, South Korea Seoul Natl Univ Hosp Seoul South Korea 110744 Seoul 110744, South Korea Seoul Natl Univ Hosp, Dept Radiol, Seoul 110744, South Korea Seoul Natl Univ Hosp Seoul South Korea 110744 Seoul 110744, South Korea Seoul Natl Univ Hosp, Dept Surg, Seoul 110744, South Korea Seoul Natl UnivHosp Seoul South Korea 110744 Seoul 110744, South Korea Seoul Natl Univ, Med Res Ctr, Inst Radiat Med, Seoul 110744, South Korea Seoul Natl Univ Seoul South Korea 110744 Med, Seoul 110744, South Korea
Titolo Testata:
RADIOLOGY
fascicolo: 1, volume: 217, anno: 2000,
pagine: 240 - 246
SICI:
0033-8419(200010)217:1<240:NBLEWP>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR ANGIOGENESIS; IN-SITU; SONOGRAPHY; CARCINOMA; MASSES; CANCER;
Keywords:
breast neoplasms, diagnosis; breast neoplasms, US; ultrasound (US), contrast media; ultrasound (US), power Doppler studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Moon, WK Seoul Natl Univ Hosp, Clin Res Inst, 28 Yongon Dong, Seoul 110744, South Korea Seoul Natl Univ Hosp 28 Yongon Dong Seoul South Korea 110744rea
Citazione:
W.K. Moon et al., "Nonpalpable breast lesions: Evaluation with power Doppler US and a microbubble contrast agent - Initial experience", RADIOLOGY, 217(1), 2000, pp. 240-246

Abstract

PURPOSE: To evaluate power Doppler ultrasonography (US) performed with a microbubble US contrast agent in the differentiation of nonpalpable breast lesions. MATERIALS AND METHODS: Fifty nonpalpable breast lesions in 50 patients were prospectively evaluated with power Doppler US before and after injection of the contrast agent SH U 508A. Lesion vascularity and the morphology of vessels on US scans were analyzed and were correlated with histologic results. RESULTS: Surgical excision revealed 22 cancers and 28 benign lesions. At nonenhanced power Doppler US, eight (36%) of 22 cancers and four (14%) of 28benign lesions were vascular. At contrast agent-enhanced power Doppler US,21 (95%) cancers and six (21%) benign lesions were vascular (P < .001). Irregular vessels were seen in three cancers and one benign lesion at nonenhanced power Doppler US and in 11 cancers and one benign lesion at contrast-enhanced power Doppler US. By using the presence of vascularity in the mass as the diagnostic criterion for malignancy, the sensitivity, specificity, and positive and negative predictive values of power Doppler US changed from36%, 86%, 67%, and 63%, respectively, to 95%, 79%, 78%, and 96% after contrast agent injection. CONCLUSION: Contrast-enhanced power Doppler US was superior nonenhanced power Doppler US in the demonstration and characterization of tumor vascularity in nonpalpable breast lesions. Contrast-enhanced power Doppler US may beuseful for the differentiation between nonpalpable breast cancers and benign tumors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 12:24:57