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Titolo:
Intracranial leptomeningeal metastases: Comparison of depiction at FLAIR and contrast-enhanced MR imaging
Autore:
Singh, SK; Agris, JM; Leeds, NE; Ginsberg, LE;
Indirizzi:
Univ Texas, MD Anderson Canc Ctr, Dept Diagnost Radiol, Houston, TX 77030 USA Univ Texas Houston TX USA 77030 pt Diagnost Radiol, Houston, TX 77030 USA
Titolo Testata:
RADIOLOGY
fascicolo: 1, volume: 217, anno: 2000,
pagine: 50 - 53
SICI:
0033-8419(200010)217:1<50:ILMCOD>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
INVERSION-RECOVERY MR; INITIAL CLINICAL-EXPERIENCE; 3D FAST FLAIR; PULSE SEQUENCE; MULTIPLE-SCLEROSIS; CARCINOMATOSIS; BRAIN;
Keywords:
brain neoplasms, MR; brain neoplasms, secondary; magnetic resonance (MR), comparative studies; magnetic resonance (MR), inversion recovery; magnetic resonance (MR), pulse sequences; meninges, neoplasms;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Singh, SK Univ Texas, MD Anderson Canc Ctr, Dept Diagnost Radiol, Box 57,1515 Holcombe Blvd, Houston, TX 77030 USA Univ Texas Box 57,1515 Holcombe Blvd Houston TX USA 77030 30 USA
Citazione:
S.K. Singh et al., "Intracranial leptomeningeal metastases: Comparison of depiction at FLAIR and contrast-enhanced MR imaging", RADIOLOGY, 217(1), 2000, pp. 50-53

Abstract

To compare contrast material-enhanced T1-weighted and fluid-attenuated inversion-recovery (FLAIR) magnetic resonance (MR) images in depicting leptomeningeal metastases. MATERIALS AND METHODS: Malignant lesions detected at cytologic examinationof of cerebrospinal fluid in 70 patients were reviewed. There were 58 studies in which both FLAIR and contrast-enhanced T1-weighted spin-echo MR images were available. A senior neuroradiologist reviewed the images from each sequence individually and separately for signs of leptomeningeal metastasesand assigned a diagnostic rating of positive, indeterminate, or negative. RESULTS: Leptomeningeal metastases were depicted in 38 cases on contrast-enhanced T1-weighted spin-echo images and in 20 cases on FLAIR images. In three cases, leptomeningeal metastases were detected:by using only FLAIR images. In 20 cases, leptomeningeal metastases were detected by using only contrast-enhanced T1-weighted spin-echo images. FLAIR imaging has a sensitivityof 34% for cytologically proved leptomeningeal metastases. Gadolinium-enhanced MR imaging has a sensitivity of 66%. CONCLUSION: Used alone, contrast-enhanced T1-weighted images are better than FLAIR images for detecting leptomeningeal metastases. This is particularly true for cases in which leptomeningeal metastases manifest primarily or solely as cranial nerve involvement.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 00:15:15