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Titolo:
Development and validity of the test for the early detection of dementia with differentiation from depression (TE4D)
Autore:
Ihl, R; Grass-Kapanke, B; Lahrem, P; Brinkmeyer, J; Fischer, S; Gaab, N; Kaupmannsennecke, C;
Indirizzi:
Univ Dusseldorf, Rhein Kliniken, Psychiat Klin, D-40629 Dusseldorf, Germany Univ Dusseldorf Dusseldorf Germany D-40629 , D-40629 Dusseldorf, Germany
Titolo Testata:
FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE
fascicolo: 9, volume: 68, anno: 2000,
pagine: 413 - 422
SICI:
0720-4299(200009)68:9<413:DAVOTT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
GER
Soggetto:
MINI-MENTAL-STATE; PRIMARY DEGENERATIVE DEMENTIA; DISEASE ASSESSMENT SCALE; COGNITIVE RATING-SCALE; CLOCK DRAWING TEST; ALZHEIMERS-DISEASE; NEUROPSYCHOLOGICAL ASSESSMENT; HOSPITAL PATIENTS; SCREENING-TEST; CONSORTIUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
56
Recensione:
Indirizzi per estratti:
Indirizzo: Ihl, R Univ Dusseldorf, Rhein Kliniken, Psychiat Klin, Berg Landstr 2, D-40629 Dusseldorf, Germany Univ Dusseldorf Berg Landstr 2 Dusseldorf GermanyD-40629 Germany
Citazione:
R. Ihl et al., "Development and validity of the test for the early detection of dementia with differentiation from depression (TE4D)", F NEUR PSYC, 68(9), 2000, pp. 413-422

Abstract

Psychometric tests used for the early detection of dementia often are seenas too difficult or too complex. Classical neuropsychologic tests were notdeveloped for this purpose. Sensitivity and specificity to descriminate "healthy" vs. "ill" are low. For measuring both dementive and depressive symptoms, so far no test has been published. The objective of this study was todevelop a sensitive and specific test for dementia that is easy to administer and to evaluate. Moreover, it should discriminate dementia from depressive pseudodementia. With respect to former studies, items were selected that recognized patients in the beginning of the disease. Additionally, depressive symptoms were rated. With the items for dementia, 88 patients with dementia of the Alzheimer type, 52 patients with depressive disorder and 37 healthy elderly controls were investigated. In this group of already diagnosed patients, the test reached a sensitivity and specificity of 100 percent (healthy elderly controls vs, patients with Alzheimer's disease: n = 125, U = 0, p < 0.001; patients with depressive disorder vs. patients with Alzheimer's disease: n = 140, U = 0, p < 0.001; healthy elderly controls vs, patients with depressive disorder: n = 89, U = 485.5, p < 0.001). For the dementia items, the inter-rater-reliability was r(s) = 0.996 (p < 0.001, n = 18),for the depression items it was r(s) = 0.753 (n = 18, p < 0.001). The test-retest-reliability was r(s) = 0.868 (p < 0.001, n = 35) for the dementia items and r(s) = 0.7 (n = 8, p < 0.05) for the depression items. These validation data will make the test useful for practitioners. Its ability to discriminate patients suffering from dementia of the Alzheimer type from healthy controls is comparable to tests consuming more time.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 11:15:35