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Titolo:
Barrett's esophagus
Autore:
Ertan, A; Younes, M;
Indirizzi:
Baylor Coll Med, Dept Med, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 Med, Dept Med, Houston, TX 77030 USA Baylor Coll Med, Dept Pathol, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 , Dept Pathol, Houston, TX 77030 USA Methodist Hosp, Houston, TX 77030 USA Methodist Hosp Houston TX USA 77030Methodist Hosp, Houston, TX 77030 USA
Titolo Testata:
DIGESTIVE DISEASES AND SCIENCES
fascicolo: 8, volume: 45, anno: 2000,
pagine: 1670 - 1673
SICI:
0163-2116(200008)45:8<1670:BE>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIGH-GRADE DYSPLASIA; P53 PROTEIN ACCUMULATION; PHOTODYNAMIC THERAPY; LASER-ABLATION; FLOW-CYTOMETRY; FOLLOW-UP; ADENOCARCINOMA; METAPLASIA; SURVEILLANCE; EPITHELIUM;
Keywords:
Barrett's esophagus; metaplasia; dysplasia; adenocarcinoma;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Ertan, A 6550 Fannin,Suite 1122, Houston, TX 77030 USA 6550 Fannin,Suite 1122 Houston TX USA 77030 ouston, TX 77030 USA
Citazione:
A. Ertan e M. Younes, "Barrett's esophagus", DIG DIS SCI, 45(8), 2000, pp. 1670-1673

Abstract

Barrett's esophagus occurs more frequently than previously anticipated. Detection of Barrett's esophagus is by endoscopic biopsy in which normal squamous epithelium of the esophagus is replaced by a specialized columnar epithelium of any length. Patients with more than five years of gastroesophageal reflux symptoms, particularly those 50 years of age or older, should haveupper endoscopy to detect Barrett's esophagus. With recognition of Barrett's esophagus as a premalignant lesion, the crucial issue is surveillance for detection of dysplasia. Although the natural history of dysplasia is incompletely defined, it is clear that patients with dysplasia have a higher risk for adenocarcinoma than those without dysplasia. Dysplasia is not the ideal marker for selecting patients at high risk for adenocarcinoma, however:recent studies have shown that p53 protein accumulation appears to be earlier and more specific/sensitive marker of malignant potential in Barrett's esophagus. Management of Barrett's esophagus often involves a multidisciplinary evaluation and its current status is reviewed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/21 alle ore 16:13:37