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Titolo:
PRE-ILLNESS DIETARY FACTORS IN INFLAMMATORY BOWEL-DISEASE
Autore:
REIF S; KLEIN I; LUBIN F; FARBSTEIN M; HALLAK A; GILAT T;
Indirizzi:
TEL AVIV SOURASKY MED CTR,DEPT GASTROENTEROL,6 WEIZMAN ST IL-64239 TEL AVIV ISRAEL TEL AVIV SOURASKY MED CTR,DEPT GASTROENTEROL IL-64239 TEL AVIV ISRAEL TEL AVIV SOURASKY MED CTR,DEPT PEDIAT GASTROENTEROL IL-64239 TEL AVIVISRAEL TEL AVIV UNIV,SACKLER FAC MED IL-69978 TEL AVIV ISRAEL
Titolo Testata:
Gut
fascicolo: 6, volume: 40, anno: 1997,
pagine: 754 - 760
SICI:
0017-5749(1997)40:6<754:PDFIIB>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
BREAST-CANCER ETIOLOGY; CROHNS-DISEASE; ULCERATIVE-COLITIS; CIGARETTE-SMOKING; CONSUMPTION; SUGAR; FIBER; FAT;
Keywords:
DIET; NUTRITION; ULCERATIVE COLITIS; CROHNS DISEASE; INFLAMMATORY BOWEL DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
S. Reif et al., "PRE-ILLNESS DIETARY FACTORS IN INFLAMMATORY BOWEL-DISEASE", Gut, 40(6), 1997, pp. 754-760

Abstract

Background-The effect of environmental factors has been demonstrated in the pathogenesis of inflammatory bowel disease (IBD). Nutrition maybe one of them. Aim-To investigate the pre-illness diet in patients with recent IBD in comparison with matched population and clinic controls. Methods-Quantified dietary histories were obtained from 87 patients with recent IBD (54 ulcerative colitis (UC) and 33 Crohn's disease (CD)) and 144 controls. Odds ratios (OR) for IBD were derived for intake levels of various foods. Results-A high sucrose consumption was associated with an increased risk for IBD (OR 2.85 (p = 0.03) against population controls and 5.3 (p = 0.00) against clinic controls). Lactose consumption showed no effect while fructose intake was negatively associated with risk for IBD (NS). Similar trends were noted in UC and CD. A high fat intake was associated with an increased risk for UC; this was particularly marked for animal fat (OR 4.09, p = 0.02) and cholesterol (OR 4.57, p = 0.02). A high intake of fluids (p = 0.04), magnesium(p = 0.04), vitamin C, and fruits (NS) was negatively associated withthe risk for IBD, while a positive association was found for retinol (p = 0.01). Most of the findings were similar in UC and CD except for potassium and vegetable consumption which showed a negative association only with risk for CD. Conclusions-An association was found between pre-illness diet and subsequent development of UC and CD. The effect of dietary components may be primary or modulatory.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:48:18