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Titolo:
Multiple-site optical recording of mouse brainstem evoked by vestibulocochlear nerve stimulation
Autore:
Yang, SM; Doi, T; Asako, M; Matsumoto-Ono, A; Kaneko, T; Yamashita, T;
Indirizzi:
Kansai Med Univ, Dept Otolaryngol, Osaka 5708507, Japan Kansai Med Univ Osaka Japan 5708507 pt Otolaryngol, Osaka 5708507, Japan Chinese PLA Gen Hosp, Dept Otolaryngol, Beijing 100853, Peoples R China Chinese PLA Gen Hosp Beijing Peoples R China 100853 853, Peoples R China
Titolo Testata:
BRAIN RESEARCH
fascicolo: 1, volume: 877, anno: 2000,
pagine: 95 - 100
SICI:
0006-8993(20000915)877:1<95:MOROMB>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEDIAL VESTIBULAR NUCLEUS; VOLTAGE-SENSITIVE DYES; POSTSYNAPTIC POTENTIALS; NEURONS; CHICK; INVITRO; STEM; TRANSMISSION; SYSTEM;
Keywords:
optical recording; voltage-sensitive dye; cochlear nucleus; vestibular nucleus; synaptic transmission; mouse; brainstem;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Doi, T Kansai Med Univ, Dept Otolaryngol, Fumizono Cho 10-15, Osaka 5708507, Japan Kansai Med Univ Fumizono Cho 10-15 Osaka Japan 5708507 8507, Japan
Citazione:
S.M. Yang et al., "Multiple-site optical recording of mouse brainstem evoked by vestibulocochlear nerve stimulation", BRAIN RES, 877(1), 2000, pp. 95-100

Abstract

We used optical imaging to investigate the mouse cochlear and vestibular nucleus in brainstem slices using a voltage-sensitive dye, RH 155. As a result, the spatiotemporal patterns of excitatory propagation were shown. Theseoptical signals consisted of two components consisting of a spike-like fast signal and a long-lasting slow signal. All responses were abolished by tetrodotoxin. The slow signals were eliminated under a Ca2+-free solution. Inaddition, synaptic fatigue was also observed. The present study indicated the feasibility of optical recording for visually revealing the synaptic transmission in both the vestibular and cochlear nucleus. (C) 2000 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:45:31