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Titolo:
The validity of self-reported drug use in non-treatment seeking individuals with cocaine dependence: Correlation with biochemical assays
Autore:
Elman, I; Krause, S; Breiter, HC; Gollub, RL; Heintges, J; Baumgartner, WA; Rosen, BR; Gastfriend, DR;
Indirizzi:
Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat,Addict Serv, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 ychiat,Addict Serv, Boston, MA 02114 USA Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Radiol,Nucl Magnet Resonance Ctr, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 gnet Resonance Ctr, Boston, MA 02114 USA Univ So Calif, Sch Pharm, Los Angeles, CA USA Univ So Calif Los Angeles CA USA o Calif, Sch Pharm, Los Angeles, CA USA W Los Angeles Vet Adm Med Ctr, Los Angeles, CA USA W Los Angeles Vet Adm Med Ctr Los Angeles CA USA tr, Los Angeles, CA USA
Titolo Testata:
AMERICAN JOURNAL ON ADDICTIONS
fascicolo: 3, volume: 9, anno: 2000,
pagine: 216 - 221
SICI:
1055-0496(200022)9:3<216:TVOSDU>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARBOHYDRATE-DEFICIENT TRANSFERRIN; HEAVY ALCOHOL-CONSUMPTION; HAIR ANALYSIS; ABUSE; METABOLITES; MARKERS; HEROIN; SERUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Elman, I Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Psychiat,Addict Serv, 15 Parkman St,WACC-812, Boston, MA 02114 USA Harvard Univ 15 Parkman St,WACC-812 Boston MA USA 02114 02114 USA
Citazione:
I. Elman et al., "The validity of self-reported drug use in non-treatment seeking individuals with cocaine dependence: Correlation with biochemical assays", AM J ADDICT, 9(3), 2000, pp. 216-221

Abstract

Accurate estimate of drug exposure plays an important role in studies of the neurobiology of drug dependence. The validity of self-reported drug use by subjects participating in such studies has not been well established. This study examined the relationship between self-reported drug use and biological markers in 18 non-treatment-seeking cocaine-dependent individuals participating in research on the effects of cocaine on the brain. A significant relationship was found between self-reported frequency of cocaine use andhair cocaine concentration. Frequency of alcohol use correlated significantly with plasma carbohydrate-deficient transferrin and aspartate aminotransferase levels. These results suggest that self-reported substance use in non-treatment seeking research subjects is generally valid.

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Documento generato il 20/09/20 alle ore 04:38:43