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Titolo:
Scintigraphic method for evaluating reductions in local blood volumes in human extremities
Autore:
Blond, L; Madsen, JL;
Indirizzi:
Hvidovre Hosp, Dept Clin Physiol & Nucl Med, Copenhagen, Denmark Hvidovre Hosp Copenhagen Denmark hysiol & Nucl Med, Copenhagen, Denmark Hvidovre Hosp, Dept Orthoped Surg, Copenhagen, Denmark Hvidovre Hosp Copenhagen Denmark ept Orthoped Surg, Copenhagen, Denmark
Titolo Testata:
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION
fascicolo: 5, volume: 60, anno: 2000,
pagine: 333 - 339
SICI:
0036-5513(200008)60:5<333:SMFERI>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIMB EXSANGUINATION; VENOUS VOLUME; FLOW; PLETHYSMOGRAPHY; HEMODYNAMICS; ELEVATION; CELLS; ANGLE;
Keywords:
exsanguination; gravitation; haemodynamics; surgery; tourniquets;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Blond, L Ehevej 9, DK-2680 Solrod, Denmark Ehevej 9 Solrod Denmark DK-2680 evej 9, DK-2680 Solrod, Denmark
Citazione:
L. Blond e J.L. Madsen, "Scintigraphic method for evaluating reductions in local blood volumes in human extremities", SC J CL INV, 60(5), 2000, pp. 333-339

Abstract

We introduce a new method for evaluating reductions in local blood volumesin extremities, based on the combined use of autologue injection of 99mTc-radiolabelled erythrocytes and clamping of the limb blood flow by the use of a tourniquet. Twenty-two healthy male volunteers participated in the experiment. Evaluation of one versus two scintigraphic projections, trials for assessment of the reproducibility, a comparison of the scintigraphic methodwith a water-plethysmographic method and registration of the fractional reduction in blood volume caused by exsanguination as a result of simple elevation were carried out. No significant differences between results obtainedby the use of one or two scintigraphic projections were found. The between-subject coefficient of variation was 14% in the lower limb experiment and 11% in the upper limb experiment. The within-subject coefficient of variation was 6% in the lower limb experiment and 6% in the upper limb experiment. We found a significant relation (r = 0.42, p = 0.018) between the results obtained by the scintigraphic method and the plethysmographic method. In fractions, a mean reduction in blood volume of 0.49 +/- 0.14 (2 SD) was foundafter 1 min of elevation of the lower limb and a mean reduction of 0.45 +/- 0.10 (2 SD) after half a minute of elevation of the upper limb. We conclude that the method is precise and can be used in investigating physiologic and pathophysiologic mechanisms in relation to blood volumes of limbs not subject to research previously.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 23:27:04