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Titolo:
A combined functional in vivo measure for primary and secondary auditory cortices
Autore:
Engelien, A; Schulz, M; Ross, B; Arolt, V; Pantev, C;
Indirizzi:
Univ Munster, Inst Expt Audiol, Biomagnetism Ctr, D-48129 Munster, GermanyUniv Munster Munster Germany D-48129 etism Ctr, D-48129 Munster, Germany Univ Munster, Dept Neurol, D-48129 Munster, Germany Univ Munster MunsterGermany D-48129 pt Neurol, D-48129 Munster, Germany Cornell Univ, Weill Med Coll, Dept Psychiat, Funct Neuroimaging Lab, New York, NY 10021 USA Cornell Univ New York NY USA 10021 uroimaging Lab, New York, NY 10021 USA Univ Munster, Dept Psychiat, D-48129 Munster, Germany Univ Munster Munster Germany D-48129 Psychiat, D-48129 Munster, Germany
Titolo Testata:
HEARING RESEARCH
fascicolo: 1-2, volume: 148, anno: 2000,
pagine: 153 - 160
SICI:
0378-5955(200010)148:1-2<153:ACFIVM>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
MIDDLE-LATENCY RESPONSES; EVOKED MAGNETIC-FIELDS; STEADY-STATE RESPONSES; CORTEX; LESIONS; SCHIZOPHRENIA; ORGANIZATION; STIMULATION; POTENTIALS; ORIGIN;
Keywords:
auditory evoked field; central auditory deficit; steady-state response; auditory cortex; magnetoencephalography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Pantev, C Univ Munster, Inst Expt Audiol, Biomagnetism Ctr, D-48129 Munster, Germany Univ Munster Munster Germany D-48129 D-48129 Munster, Germany
Citazione:
A. Engelien et al., "A combined functional in vivo measure for primary and secondary auditory cortices", HEARING RES, 148(1-2), 2000, pp. 153-160

Abstract

Auditory evoked magnetic fields are reliable physiological in vivo markersof activity generated in auditory cortices. In recent years, several components of auditory evoked fields have been demonstrated with specific topographies within the auditory cortex in man. Their differential elicitation and analyses has rendered the discrimination of neural activities in primary vs. secondary auditory cortical fields possible. This in vivo measure may be of interest in a number of (neuro)psychiatric and neuropsychological disorders with central auditory deficits, in which in vivo anatomical measures do not allow a clear distinction of primary vs. secondary auditory cortex involvement. To help better understand the pathophysiology of such disorders, we developed and introduce a combined measure of steady-state field (SSR)and the N1 component of the transient evoked field. The acoustic stimulus for this paradigm consists of a 500-ms tone burst with 39-Hz amplitude modulation of the carrier frequency. This combined stimulation allows assessment of both auditory cortex components in one brief examination to be well tolerated by patients. We examined the source locations of SSR and N1 component with separate classical stimulation and combined stimulation within-session in healthy volunteer subjects. We demonstrate here that the distinct sources of steady-state (primary auditory cortex) and N1 (secondary auditory cortex) responses can be reliably measured without significant spatial distortion with this combined stimulation paradigm. (C) 2000 Elsevier Science B. V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 07:34:41