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Titolo:
Combination therapy with transcatheter arterial chemoembolization and percutaneous microwave coagulation therapy for hepatocellular carcinoma
Autore:
Seki, T; Tamai, T; Nakagawa, T; Imamura, M; Nishimura, A; Yamashiki, N; Ikeda, K; Inoue, K;
Indirizzi:
Kansai Med Univ, Dept Internal Med 3, Moriguchi, Osaka 5708507, Japan Kansai Med Univ Moriguchi Osaka Japan 5708507 guchi, Osaka 5708507, Japan
Titolo Testata:
CANCER
fascicolo: 6, volume: 89, anno: 2000,
pagine: 1245 - 1251
SICI:
0008-543X(20000915)89:6<1245:CTWTAC>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
ETHANOL INJECTION THERAPY; BLOOD-FLOW; LIVER; ABLATION; NECROSIS;
Keywords:
percutaneous microwave coagulation therapy; hepatocellular carcinoma; transcatheter arterial chemoembolization; local recurrence;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Seki, T Kansai Med Univ, Dept Internal Med 3, 10-15 Fumizonocho, Moriguchi, Osaka 5708507, Japan Kansai Med Univ 10-15 Fumizonocho Moriguchi Osaka Japan 5708507 an
Citazione:
T. Seki et al., "Combination therapy with transcatheter arterial chemoembolization and percutaneous microwave coagulation therapy for hepatocellular carcinoma", CANCER, 89(6), 2000, pp. 1245-1251

Abstract

BACKGROUND. A small number of microwave electrode insertions and microwaveirradiations were used to obtain complete tumor necrosis in hepatocellularcarcinomas (HCC) measuring > 2.0 cm but less than or equal to 3.0 cm in greatest dimension. The efficacy of combining transcatheter arterial chemoembolization (TACE) with subsequent percutaneous microwave coagulation therapy(PMCT) was assessed in this study. METHODS. Eighteen patients with cirrhosis and HCCs measuring > 2.0 cm but less than or equal to 3.0 cm in greatest dimension underwent TACE followed within 1-2 days by ultrasonographically guided PMCT. RESULTS. On dynamic computed tomography, 17 of the 18 patients showed complete necrosis of their tumor lesions and the treated tumor margins (greaterthan or equal to 5 mm). Necroses of tumors and noncancerous margins surrounding the tumors were obtained using 4 microwave irradiations (1 session) in 14 patients, 5 microwave irradiations (2 sessions) in 2 patients, and 6 microwave irradiations (2 sessions) in 1 patient. The follow-up period was short (12-31 mos), and all patients remained alive. No local recurrences in the treated areas were detected. No fatal complications were observed. Pleural effusion was observed in 1 patient only. CONCLUSIONS. This combined therapy of PMCT applied within 1-2 days of TACEeffectively treated HCCs measuring > 2.0 cm but less than or equal to 3.0 cm in greatest dimension. A small number of microwave electrode insertions and microwave irradiations were used. (C) 2000 American Cancer Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 14:22:00